نتایج جستجو برای: pc12 tet off cells pto

تعداد نتایج: 1558925  

2008
Kim U. Wittrup-Jensen Kjeld M. Pedersen

Background. The Person Trade-Off (PTO) method is a preference-based evaluation technique that

2016
Atze T. Das Liliane Tenenbaum Ben Berkhout

The tetracycline-controlled Tet-Off and Tet-On gene expression systems are used to regulate the activity of genes in eukaryotic cells in diverse settings, varying from basic biological research to biotechnology and gene therapy applications. These systems are based on regulatory elements that control the activity of the tetracycline-resistance operon in bacteria. The Tet-Off system allows silen...

Journal: :iranian journal of basic medical sciences 0
mahdi mojarrab pharmaceutical sciences research center, school of pharmacy, kermanshah university of medical sciences, kermanshah, iran mehran mehrabi students research committee, kermanshah university of medical sciences, kermanshah, iran farahnaz ahmadi pharmaceutical sciences research center, school of pharmacy, kermanshah university of medical sciences, kermanshah, iran leila hosseinzadeh pharmaceutical sciences research center, school of pharmacy, kermanshah university of medical sciences, kermanshah, iran

objective(s): this study was designed to indicate whether different fractions from artemisia biennis hydroethanolic extract could provide cytoprotection against oxidative stress and apoptosis induced by doxorubicin (dox) in rat pheochromocytoma cell line (pc12). material and methods:cell viability was determined by mtt assay. also, activation of caspase-3 and superoxide dismutase were evaluated...

2013
Rico H. Hansen Morten M. Kramer Enrique Vidal

The Wavestar Wave Energy Converter (WEC) is a multiple absorber concept, consisting of 20 hemisphere shaped floats attached to a single platform. The heart of the Wavestar WEC is the Power Take-Off (PTO) system, converting the wave induced motion of the floats into a steady power output to the grid. In the present work, a PTO based on a novel discrete displacement fluid power technology is expl...

Journal: :Cancer research 2004
Kayo Yoshida Takashi Morita

The mouse histone H2AX has unique COOH-terminal serine residues that are phosphorylated in response to double-strand DNA breaks introduced by ionizing radiation. This suggests that H2AX acts to maintain genomic stability. We constructed a tetracycline (tet)-directed turn-off vector and integrated it into F9 mouse teratocarcinoma cells by homologous recombination. In homozygously recombined cell...

2015
Grégory S. Payne Rémy Pascal Guillaume Vaillant

A free-floating wave energy converter (WEC) concept whose power take-off (PTO) system reacts against water inertia is investigated herein. The main focus is the impact of inclining the PTO direction on the system performance. The study is based on a numerical model whose formulation is first derived in detail. Hydrodynamics coefficients are obtained using the linear boundary element method pack...

2005
R. S. Thomas D. R. Buckmaster

Nearly all tractor PTO arrangements used today consist of a rotating mechanical shaft with two or more universal joints. This arrangement continues to be an entanglement hazard. By driving the attachment with fluid power, this hazard could be eliminated. This project included the design, development, and testing of an experimental tractor based on a John Deere 4040. The entire power train was t...

Journal: :physiology and pharmacology 0
saeed esmaeili-mahani department of biology, faculty of sciences, shahid bahonar university of kerman, kerman, iran zahra hajializadeh laboratory of molecular neuroscience, kerman neuroscience research center, kerman university of medical sciences, kerman, iran shima torkzadeh-mahani laboratory of molecular neuroscience, kerman neuroscience research center, kerman university of medical sciences, kerman, iran

introduction: g-proteins have an important role in the cell signaling of numerous receptors. the situation of g-proteins in health and disease and their critical role in the development of diabetic side effects is an interested scientific field. here, the changes in the expression of g-protein subunits (gαi, gαs and gβ) were evaluated in hyperglycemic situation of pc12 cells as a cellular model...

ژورنال: Anatomical Sciences Journal 2008
Davari Zanjani , Maryam, Azadbakht , Mehri, Amini , Ali, Hill, Mark, Sadri, Soheil,

Purpose: The present study was designed to investigate the effect of hydrostatic pressure on cell viability, apoptosis induction, morphology and cell-substrate interactions of PC12 cells. Materials and Methods: PC12 as a neuronal cell line maintained in RPMI 1640 culture medium supplemented with 10% fetal bovine serum. PC12 cells were subjected to hydrostatic pressure. Experimental pressure con...

ژورنال: کومش 2019
Aminzadeh, Azadeh, Fallah , Fahimeh ,

Introduction: Parkinson's disease (PD) is a common neurodegenerative disorder characterized by progressive neuronal dysfunction. Growing evidence has shown that oxidative stress plays a crucial role in the pathogenesis of Parkinson's disease. Correspondingly, the current study evaluated the protective effect of topiramate in 6-hydroxydopamine induced oxidative stress and apoptosis in PC12 cells...

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