Substitution reactions of the complexes [Pd(bpma)(H2O)]2+ and [Pt(bpma)(H2O)]2+, where bpma = bis(2-pyridylmethyl)amine, with TU, DMTU and TMTU for both complexes and Cl-, Br-, I- and SCN- for the platinum complex, were studied in aqueous 0.10 M NaClO4 at pH 2.5 using a variable-temperature stopped-flow spectrophotometer. The pKa value for the coordinated water molecule in [Pd(bpma)(H2O)]2+ (6....

Clean production of hydrogen from electrochemical water splitting has been known as a green method of fuel production. In this work, electrocatalytic hydrogen evolution reaction (HER) was investigated at new prepared layered double hydroxides (LDH) in acidic solution. NiAl/carbon black (CB) LDH was monitored using x-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectroscopy, scannin...

BURG, MAURICE, AND NORDICA GREEN. Function of the thick ascending limb of Henle’s loop. Am. J. Physiol. 224(3) : 659-668. 1973.-The thick ascending limb of Henle’s loop was dissected from rabbit kidneys and perfused in vitro. There was net NaCl absorption from the tubule lumen with resultant lowering of lumen NaCl concentration below that of the bath. Since the electrical PD was positive in the...

BACKGROUND AND PURPOSE The LRRK2 (PARK8; OMIM607060) substitution was recently identified as a causative mutation for Parkinson's disease (PD). The pathologic heterogeneity of LRRK2-positive patients suggests that mutation of the LRRK2 gene is associated with the pathogenesis of PD and Parkinson-plus disorders, such as multiple system atrophy (MSA). We previously reported that the G2019S LRRK2 ...

Palladium zinc aluminium (2.28/10.37/0.35), Pd(2.28(1))Zn(10.37(1))Al(0.35(1)), represents the upper limit of Al substitution into the parent cubic γ-brass Pd(2+x)Zn(11-x). The structure can be described in terms of a 26-atom cluster consisting of an inner tetra-hedron (IT), an outer tetra-hedron (OT), an octa-hedron (OH) and a cubocta-hedron (CO), with the substituted Al atoms partially occupy...

Pd/C in HFIP was used to hydrogenate indole derivatives under relatively mild conditions, leading to potential synthetic intermediates of bioactive compounds. Depending on their substitution, tetrahydroindoles or octahydroindoles could selectively be obtained.

BACKGROUND Mutations in parkin are estimated to account for as much as 50% of familial Parkinson disease (PD) and 18% of sporadic PD. Single heterozygous mutations in parkin in both familial and sporadic cases may also increase susceptibility to PD. To our knowledge, all previous studies have been restricted to PD cases; this is the first study to systematically screen the parkin coding regions...