BACKGROUND AND PURPOSE In 2001, pediatric radiologists participating in a panel discussion on CT dose reduction suggested that approximately 30% of head CT examinations were performed unnecessarily. With increasing concern regarding radiation exposure to children and imaging costs, this claim warrants objective study. The purpose of this study was to test the null hypothesis that 30% of head CT...

Graves' disease (GD) accounts for a large proportion of pediatric hyperthyroidism, and the first-line treatment is antithyroid drug (ATD) therapy. Methimazole (MMI) is effective in most patients but is associated with significant adverse events (AEs). We reviewed the medical records of GD patients (n = 56) with onset age of <15 yr and investigated the relationship between MMI dose and AEs. The ...

Major Guidelines Changes Changes in the pediatric section of the International Guidelines 2000 generally represent qualifications and refinements rather than major paradigm shifts from the 1992 Guidelines.1 The new guidelines continue to emphasize prevention of cardiac arrest. Pediatric BLS guidelines detail specific modifications of adult techniques necessary to address anatomic, physiological...

Major Guidelines Changes Changes in the pediatric section of the International Guidelines 2000 generally represent qualifications and refinements rather than major paradigm shifts from the 1992 Guidelines.1 The new guidelines continue to emphasize prevention of cardiac arrest. Pediatric BLS guidelines detail specific modifications of adult techniques necessary to address anatomic, physiological...

Major Guidelines Changes Changes in the pediatric section of the International Guidelines 2000 generally represent qualifications and refinements rather than major paradigm shifts from the 1992 Guidelines.1 The new guidelines continue to emphasize prevention of cardiac arrest. Pediatric BLS guidelines detail specific modifications of adult techniques necessary to address anatomic, physiological...

Background: Increasing the x-ray focus to film distance (FFD) has been advocated as an effective method to reduce the patients’ radiation dose. The aim of this study was to investigate the efficacy of this technique in patients' dose and image quality in pediatric chest x-ray.Material and methods: Sixty pediatric patients were x-ray imaged at FFDs of 100 and 130 cm. Dose measurements were perfo...

The practice of pediatric critical care medicine has matured dramatically during the past decade. These guidelines are presented to update the existing guidelines published in 1993. Pediatric critical care services are provided in level I and level II units. Within these guidelines, the scope of pediatric critical care services is discussed, including organizational and administrative structure...

BACKGROUND Over the last decade, a number of clinical practice guidelines that include guidance for the management of pediatric asthma have been introduced. The consistency across pediatric asthma guidelines is unknown and the emphasis on establishing asthma control may vary. The objective of this paper was to depict the evolution of guidelines for pediatric asthma and to compare current intern...

©2003. Photo Courtesy of Meridian Medical Technologies, Inc. F ollowing the FDA’s approval of a pediatric dosage Atropen®, the Pediatric Expert Advisory Panel was asked to review the existing guidelines and recommendations regarding the treatment of children exposed to nerve agents and the Mark-1 Kit; review the new literature on pediatric nerve agent exposure; and to develop recommendations an...

This Comment argues that the parties to the International Conference on Harmonization of Technical Requirements for Regulation of Pharmaceutical Drugs (ITCH) should adopt more specific guidelines for pediatric research than those included in its Good Clinical Practice Guidelines (ICH GCP), and analyzes their attempt to do so in the Draft Guideline on Pediatric Trials. Part I of this Comment out...