Several members of the phthalate ester family have antiandrogenic properties, yet little is known about how exposure to these ubiquitous environmental contaminants early in development may affect sexual development. We conducted experiments to determine effects of in utero and lactational exposure to the most prevalent phthalate ester, di(2-ethylhexyl) phthalate (DEHP), on male reproductive sys...

Penile agenesis or aphallia is a rare congenital anomaly occurring with a frequency of 1:10 -1:30 million newborns. Fewer than 100 cases have been reported worldwide. Associated urogenital malformations and the presence of oligohydramnios with pulmonary hypoplasia determine the infant's viability. Extra-urogenital anomalies have been described in the cardiovascular, gastro-intestinal and muscul...

primary malignant lymphoma of the male external genitalia is extremely rare and it is even rarer in the penis. because of its rarity, the possibility of delay in diagnosis and mismanagement is always there. it can present as a nodule, non-healing ulcer, stricture urethra or periurethral abscess. we report a case presenting first a nodule and later on as a non-healing ulcer which was diagnosed b...

Hypospadias results from abnormal development of the penis that leaves the urethral meatus proximal to its normal glanular position. Meatal position may be located anywhere along the penile shaft, but more severe forms of hypospadias may have a urethral meatus located at the scrotum or perineum. The spectrum of abnormalities may also include ventral curvature of the penis, a dorsally redundant ...

background:several investigations showed cartilaginouscells in fibrous tissue of the free part of the penis in one humpedcamel. objectives: the aim of this study was accurate assessmentof existence of cartilaginous cells in penis shaft of onehumpedcamel. methods: six camel penises from maturedcamels more than 3 years-old were collected from an abattoir.different specimens were prepared from eac...

A congenital prepubic sinus is a tract that originates in the skin and overlays the base of the penis; however, its embryologic basis is still debated. We herein present a case involving a 3-year-old boy who was admitted for examination of overlying tissue located a few centimeters distal to the dorsal base of the penis. Examination revealed a tiny sinus in the prepubic area, and 3 cm of tissue...

Bilateral femoral agenesis is a rare anomaly.  To the best of our knowledge, only three cases of simple congenital anomaly and three cases associated with femoral facial syndrome have been reported.  Here, we describe a simple form of bilateral femoral agenesis observed in one of the 2 dead fetuses delivered after termination of a 24-week twin pregnancy of a normal mother.  Post-mortem x-ray ex...