BACKGROUND The purpose of this study was to analyze the bacterial diversity in persistent apical lesions on root-filled teeth by using culture-independent molecular methods. DESIGN Twenty surgically removed apical lesions from therapy-resistant teeth were examined for the presence of bacterial DNA using PCR targeting the 16s ribosomal RNA gene, followed by cloning and sequencing. RESULTS Ba...

Most periapical lesions resolve after root canal treatment of teeth with primary infections. Over the last decade there has been a renewed focus on post-treatment apical periodontitis and its etiology. This review describes the microbiota associated with persistent post-treatment infection, including microbial identification, ecology, and environmental selection. Compared with untreated teeth, ...

Stem cells are the pluripotent cells that have the capacity to differentiate into other specialized cells. Recently, many experiments have been conducted to study the potentiality of stem cells in the tissue regeneration. We report two cases treated utilizing stem cells from human exfoliated deciduous teeth (SHED) in the management of periapical lesions in permanent teeth. Two normal human deci...

The objective was to evaluate the clinical efficacy of chemomechanical preparation of the root canals with sodium hypochlorite and interappointment medication with calcium hydroxide in the control of root canal infection and healing of periapical lesions. Fifty teeth diagnosed with chronic apical periodontitis were randomly allocated to one of three treatments: Single visit (SV group, n = 20), ...

Teeth may require further management following root canal treatment because of persisting or new apical pathosis. Management must be based on the diagnosis of the presenting condition and the history of the previous treatment, particularly in relation to when it was completed. Most root-filled teeth with periapical pathosis should be re-treated in the first instance via a conventional orthograd...

INTRODUCTION Endodontic retreatment is a complex intervention that requires detailed analysis of possible reasons for failure, and flawless practical execution of the procedure. OBJECTIVE The aim of the study was to assess the outcome of endodontic retreatment based on clinical and radiographic criteria after a two-year observation period. METHODS Clinical study included 49 teeth indicated ...

This in vivo study investigated the time of degradation of root filling material (trans 1,4-polyisoprene) retrieved from endodontically treated teeth and correlated the occurrence of degradation with the longevity of endodontics. Thirty-six root-filled teeth with different filling times (2 to 30 years) and with and without periapical lesions were selected. All teeth presented clinical indicatio...

OBJECTIVES The aim of this study was to assess the prevalence of periapical lesions in root canal-treated teeth in a Turkish Cypriote population and to investigate the influence of the quality of root canal fillings and coronal restorations on the prevalence of periapical lesions. SUBJECTS AND METHODS The sample for this cross-sectional study consisted of 1,006 adult patients seeking routine ...

Apical (periapical) infections of cheek teeth (CT) are a major clinical problem, especially in younger horses, where the infection inevitably involves the supporting mandibular (Fig. 1) or maxillary bones (Fig. 2), or the overlying paranasal sinuses. The term apical infection is preferable to tooth root infection as these infections often occur in younger horses before any true roots (enamel-fr...