AIM To monitor and compare the outcome of periradicular surgery in teeth that had previously undergone surgical treatment versus teeth that were undergoing a surgical procedure for the first time. METHODOLOGY A total of 164 patients with 231 roots with previously unresolved periapical lesions were followed for up to 5 years following surgery. In all, 162 roots had received unsuccessful conven...

Periapical surgery has largely improved at all levels due to new technologies provided by researchers throughout the last years. The aim of this article is to carry out a bibliographic revision of the last seven years. For this reason, we will analyse the studies published in Medline and the most important Spanish dental magazines. The subjects to investigate are mainly based on the incorporati...

BACKGROUND/AIM Matrix metalloproteinases (MMPs) are proteolytic enzymes capable of degrading almost all extracellular matrix and basement membrane components in many destructive pathological processes, such as chronic inflammation and bone-destructive lesions. The aim of this study was to determinate the correlation between concentration of collagenases (MMP-1, -8, -13) in chronic periapical le...

BACKGROUND Leptin, initially described as an adipocyte-derived hormone to regulate weight control, is expressed in normal and inflamed human dental pulp, being up-regulated during pulp experimental inflammation. Leptin receptor (LER) has been identified in human periapical granulomas. The aim of this study was to analyze and characterize the expression of leptin in human periapical granulomas. ...

AIM To report a case of conservative nonsurgical management of periapical lesions. BACKGROUND Small periapical lesions of endodontic origin usually heal by conventional endodontic therapy alone. Larger periapical lesions presumed to be cystic may require additional treatment protocols to aid in regression. Conservative nonsurgical management of such lesions eliminates the possible complicatio...

OBJECTIVES Our aim was to compare periapical radiography and cone beam CT (CBCT) for assessment of the periapical bone defect 1 week and 12 months after root-end resection. METHODS 50 patients (58 teeth) with a persisting apical periodontitis in a root-filled tooth (incisor, canine or premolar) were treated with root-end resection. 1 week and 12 months post-operatively, a CBCT scan (NewTom 3G...

Introduction. This paper describes a case of bone augmentation with combination of Platelet-Rich Fibrin (PRF) and β-TCP for treatment of chronic periapical cyst. The case was followed for 12 months. Methods. Patient presented with chronic periapical lesion in maxillary anterior teeth with history of trauma 8 years back. Radiographically, a periapical cyst was seen in relation to maxillary left ...

Introduction: Mineral trioxide aggregate (MTA) has a variety of possible uses, including root-end filling material due to its excellent sealing ability in the presence of moisture and a high degree of biocompatibility. Aim: This case report demonstrates the use of MTA as an obturating material to promote periapical healing of root canals with large apical rarefactions. Materials and Methods: An...