BACKGROUND The measurement of mechanosensitivity is a key method for the study of pain in animal models. This is often accomplished with the use of von Frey filaments in an up-down testing paradigm. The up-down method described by Chaplan et al. (J Neurosci Methods 53:55-63, 1994) for mechanosensitivity testing in rodents remains one of the most widely used methods for measuring pain in animals...

BACKGROUND The Oxford Knee Score (OKS) is a short patient-reported outcome instrument that measures pain and physical activity related to knee osteoarthritis. The purpose of this study is to evaluate, construct validity and consistent reliability of the Persian version of the OKS. METHODS The case series consisted of 80 patients who were clinically diagnosed with having knee osteoarthritis. A...

This paper sheds light on two problems in the Penn World Table (PWT) GDP estimates. First,we show that these estimates vary substantially across different versions of the PWT despitebeing derived from very similar underlying data and using almost identical methodologies; thatthis variability is systematic; and that it is intrinsic to the methodology deployed by the PWT toest...

A Plane-Wave-Transformer (PWT), integrated photoinjector operating at an X-band frequency (8.547GHz) is being developed by DULY Research Inc. in a DOE SBIR project, in collaboration with UCLA and UCD/ILSA. Upward frequency scaling from an S-band PWT photoinjector would result in a compact photoinjector with unprecedented brightness. Challenging technological innovations are required at X-band. ...

BACKGROUND Baecke Habitual Physical Activity Questionnaire (BHPAQ) has widely been employed in clinical and laboratorial studies as a tool for measuring subjects' physical activities. But, the reliability and validity of this questionnaire have not been investigated among Persian speakers. OBJECTIVES Therefore, the aim of the current study was examining the reliability and validity of the Per...

The aim of this study was to examine the role played by substance P and calcitonin gene-related peptide (CGRP) within the dorsal horn of the spinal cord in engagement of antinociception evoked by dexmedetomidine (DEX). Paw withdrawal threshold (PWT) to mechanical stimulation was determined after chronic intrathecal infusion of DEX and enzyme-linked immunosorbent assay (ELISA) was employed to ex...

It has become increasingly apparent that the pain threshold of females and males varies in an estrogen dependent manner. To investigate the modulation of pain by estrogen and the molecular mechanisms involved in this process. A total of 48 rats were ovariectomized (OVX). At 14 and 20 days after OVX, rats were divided into eight groups: groups 1-4 were administered drugs intravenously (IV); grou...

We report on the initial operation of a novel compact rf linac — the plane wave transformer (PWT). The PWT is a 42 cm long, 8 cell standing-wave structure, operated at Sband, in a π−mode. We present the properties of this linac at rf power levels from 4 MW to 8 MW and beam energy from 7 MeV to 10 MeV, measured initially using both dark current and photo-electrons. Some technical issues associat...

A novel, compact RF linac structure, the plane wave transformer (PWT), is studied. The PWT provides high accelerating field and high efficiency, and can be used to accelerate high-brightness beams. PWT linac prototypes with eight cells at S-band have been developed at UCLA and successfully used to accelerate an electron beam by more than 10 MeV in 40 cm. In this paper, we describe the principal...

BACKGROUND Fear of falling may be related to falling during stroke onset. The Fall Efficacy ScaleInternational (FES-I) with excellent psychometric properties, is an instrument developed to assess patients' concerns about fallings. The aim of this study was to determine validation of this scale in Iranian patients with stroke. METHODS The "forward-backward" procedure was applied to translate t...