Contributors Publication dates Originally released September 2, 1994; last updated June 7, 2010; expires June 7, 2013 Synonyms Stiff-man syndrome Key points • Stiff-person syndrome is a rare disorder that causes continuous muscle contraction with spasm, abnormal postures, and progressive disability. • Stiff-person syndrome is often associated with other autoimmune signs and symptoms as well as ...

Stiff-person syndrome is an autoimmune syndrome defined by muscle spasms and rigidity of proximal and axial muscles. Glutamic acid decarboxylase is the autoantigen found in 60%–80% of stiff person syndrome patients. Stiff person syndrome, cerebellar variant was characterized in a subpopulation of patients (5 of 38) with stiff person syndrome and concomitant cerebellar dysfunction and confirmed ...

objectives: stigma is a negative value. many behaviors are to ward stigmatized people. down syndrome is one of conditions with stigma. the aim of this study is to determine the sources of labeling in iranian down syndrome. methods: the view of 105 down syndrome families concerning stigma were conducted. all of down syndrome was under 50 years. results: a fair proportion of down syndrome familie...