embolism, rlheuniiatic heart disease, and periphlleral arteriopathies. During 1942 at various times I talked about the possibility of utilizinog Dicumnarol ini acute coronary thromI)osis with iivo(car(lial infarctioni with Nelson Barker, Wilbur Duryve, Irvinog Wright, and others. Considerable doubt was expressed as to the likely results, but it was agreed that a (linical trial would be worthwhi...