The PFA-100 (platelet function analyzer) is a relatively new tool for the investigation of primary hemostasis. This article reviews the history of the PFA-100 and details its clinical utility in several settings. The PFA-100 was first introduced to us in 1995 in an issue of Seminars in Thrombosis And Hemostasis, which included data from a field trial headed by Dr. Eberhard Mammen. Since that ti...

Probabilistic finite automata (PFA) model stochastic languages, i.e. probability distributions over strings. Inferring PFA from stochastic data is an open field of research. We show that PFA are identifiable in the limit with probability one. Multiplicity automata (MA) is another device to represent stochastic languages. We show that a MA may generate a stochastic language that cannot be genera...

OBJECTIVE Percutaneous treatment of an abdominal aortic aneurysm (AAA) is feasible, but is associated with a unique set of risks. A comparison of Excluder endograft deployment with femoral artery cutdown (FAC) versus percutaneous femoral access (PFA) for treatment of infrarenal AAA was undertaken. METHODS A single-institution, controlled, retrospective review was carried out in patients who u...

OBJECTIVE The goal of this study was to identify the frequency of physician-diagnosed food allergies among 6-year-old US children and study the impact of exclusive breastfeeding and complementary food introduction on this frequency. METHODS Data were analyzed from children who participated in the Infant Feeding Practices Study II Year 6 Follow-Up Study (Y6FU). Children with probable food alle...

Malaria is a parasitic disease that remains a global health burden. The ability of the parasite to rapidly develop resistance to therapeutics drives an urgent need for the delivery of new drugs. The Medicines for Malaria Venture have compounds known for their antimalarial activity, but not necessarily the molecular targets. In this study, we assess the ability of the "MMV 400" compounds to inhi...

Two experiments evaluated the ability of maternal fatty acid supplementation to alter conceptus and endometrial fatty acid composition. In Exp. 1, treatments were 1) the control, a corn-soybean meal diet; 2) flax, the control diet plus ground flax (3.75% of diet); and 3) protected fatty acids (PFA), the control plus a protected fish oil source rich in n-3 PUFA (Gromega, JBS United Inc., Sherida...

Introduction: Profunda femoris artery (PFA) normally originates from posterolateral aspect of femoral artery and circumflex arteries arise from profunda femoris artery near its origin. As femoral artery (FA) & PFA are commonly assessed for various procedures for diagnosis and treatment for many diseases, knowledge of its course and branching pattern is very important for clinicians to prevent c...

This technical note illustrates that some of the differences that have been reported regarding wheelchair propulsion may be due to the methods used to calculate key variables. Wheelchair ambulation is a very important form of locomotion that lacks a standard pushrim force and moment analysis system. We have developed tools for analyzing upper limb biomechanics during manual wheelchair propulsio...

Patellofemoral osteoarthritis (PFOA) can be associated with anterior knee pain, stiffness, and functional impairment. Some authors report that PFOA affects approximately 9% of patients older than 40 years with a greater prevalence in females. Etiology of PFOA is multifactorial and is related to the presence of abnormal stresses at the PF joint due to knee- and patient-related factors. The need ...

OBJECTIVES To report the repeatability and reproducibility of four different anatomical proximal femoral axis (a-PFA) methods for measuring anatomical lateral distal femoral angle (a-LDFA), and to compare a-LDFA values produced by each method at three different femoral elevation angles. METHODS Digital radiographs were obtained of seven dry canine femora at 0°, 12.5° and 25° elevations. Using...