The aim of this study is pharmacochemistry of Iranian flora Artemisia sieberi and its antimalarial effects on Plasmodium berghei in vivo. This is the first application of A. sieberi for treatment of murine malaria. A. sieberi were collected at flowering stage from the Khorassan and Semnan provinces of Iran; the aerial parts were air-dried at room temperature and then powdered. The powder was ma...

Identifying the molecular targets for the beneficial effects of active small-molecule compounds simultaneously is an important and currently unmet challenge. In this study, we firstly proposed network analysis by integrating data from network pharmacology and metabolomics to identify targets of active components in sini decoction (SND) simultaneously against heart failure. To begin with, 48 pot...

BACKGROUND The aim of this study was to evaluate the antimalarial effects of Iranian flora Artemisia khorassanica against Plasmodium bergheiin vivo and pharmacochemistry of its natural components. METHODS The aerial parts of Iranian flora A. khorasanica were collected at flowering stage from Khorassan Province, northeastern Iran in 2008. They were air-dried at room temperature; powder was mac...

Aims: This study aimed to evaluate and compare the in vitro anti-plasmodial cytotoxic effect of methanolic extracts from leaves, stem bark roots Annickia affinis.
 Study Design: is an experimental study.
 Place Duration Study: The work was conducted at Pharmacochemistry Natural Substances Laboratories Faculty Medicine Pharmaceutical Sciences, University Douala for extraction Biomedica...

Bentonite clays are broadly employed in the design of varied drug delivery systems due to their characteristic feature such as adsorption, swelling ability and biocompatibility. Combination polymers with clay particles considerably improve mechanical physical properties, - encapsulation efficiency controlled release behavior hybrids comparing starting components. One priority research areas at ...

OBJECTIVE To more scientifically and reasonably control the quality of Huangqi Granules, preliminary studies on the pharmacodynamics and serum pharmacochemistry of this medicine were performed. DPPH and MTT experiments showed that water extracts of Huangqi Granules had good antioxidant activity and increased immunity. Timed blood samples collected 5 min, 15 min, and 30 min after oral administra...

Aims: Schumanniophyton magnificum is a plant reputed traditionally to treat numerous urogenital infections linked several germs, notably: Escherichia coli, Staphylococcus aureus, Neisseria gonhorhea, Treponema palidum, Candida albican. This study aims evaluate and compare the in vitro antibacterial cytotoxic activities of leaves, trunk roots S. order determine parts displaying best activity.&#x...