OBJECTIVES/HYPOTHESIS Local residual or recurrent pharyngeal cancer after definitive radiotherapy (RT) or chemoradiotherapy (CRT) is correlated to poor prognosis. We analyzed the efficacy of salvage surgery for patients with local residual or recurrent pharyngeal cancer after RT or CRT. STUDY DESIGN Retrospective clinical study with chart review. METHODS Between 2001 and 2011, we treated 20...

Oral and pharyngeal cancers are strongly related to alcohol drinking. We combined findings from all case-control and cohort studies published up to September 2009 and presented analyses by subsites, using a meta-analytic approach. Summary measures were obtained using random-effects models, and taking into account the correlation between estimates from the same study. We also performed a dose-ri...

OBJECTIVE Laryngopharyngeal reflux may cause significant morbidity in the head and neck cancer population. The goal was to determine if pharyngeal reflux is increased as a result of treatment for laryngeal cancer. STUDY DESIGN A prospective clinical trial. SETTING Tertiary care center. SUBJECTS Head and neck cancer patients treated at LSU Health-Shreveport with a plan for total laryngecto...

Because we found UV-exposed oral tissue cells have reduced DNA repair and apoptotic cell death compared with skin tissue cells, we asked if a correlation existed between personal UV dose and the incidences of oral and pharyngeal cancer in the United States. We analyzed the International Agency for Research on Cancer's incidence data for oral and pharyngeal cancers by race (white and black) and ...

Citation: Djordjevic G, Dagovic A, Ristic V, Kanjevac T, Brajkovic D and Popovic M (2017) Trends and Patterns of Disparities in Oral Cavity and Pharyngeal Cancer in Serbia: Prevalence and Economic Consequences in a Transitional Country. Front. Pharmacol. 8:385. doi: 10.3389/fphar.2017.00385 Trends and Patterns of Disparities in Oral Cavity and Pharyngeal Cancer in Serbia: Prevalence and Economi...

............................................................................ 5 LIST OF ORIGINAL PUBLICATIONS ............................................... 6 ABBREVIATIONS ....................................................................... 7 INTRODUCTION ........................................................................ 8 REVIEW OF THE LITERATURE ........................................

BACKGROUND The prognostic value of cancer testis antigens in pharyngeal cancer is understudied. METHODS We recruited 90 patients who were treated for pharyngeal cancer. Monoclonal antibodies 57B and B9.8.1.1 were used for detection of MAGE-A and NY-ESO-1 genes. RESULTS MAGE-A and NY-ESO-1 gene products were detectable in 70.0% and 33.3% of pharyngeal tumors, respectively. No correlation was...

OBJECTIVE To analyze the trend of oral and pharyngeal cancer mortality rates in the period of 2002 to 2013 in Brazil according to sex, anatomical site, and macroregion of the country. METHODS The mortality data were obtained from the Mortality Information System and the population data were obtained from the Brazilian Institute of Geography and Statistics. The trend of the rates standardized ...