Objective: We present a statistical model for extracting physiologic characteristics from electrodermal activity (EDA) data in observational settings. Methods: based our on the integrate-and-fire physiology of sweat gland bursts, which predicts inverse Gaussian (IG) inter-pulse interval structure. At core model-based paradigm is subject-specific amplitude threshold selection process EDA pulses ...

Synopsis A multicompartmental tracer kinetic model permits analysis of 3D MR renography data in terms of physiologic parameters such as glomerular filtration rate. Validation studies were performed in nine subjects, in whom single kidney GFR measurements were measured using radionuclide clearance methods. Agreement between model-fit values of SKGFR and reference values was high (r=0.77). Other ...

The use of physiologic monitoring (e.g., cardiac monitoring) as an important component in providing safe patient care has escalated over the past two decades. It enables the clinician to detect physiologic changes in the patient's condition before they become clinically significant, thus allowing anticipation and prevention of adverse events. Issues and concerns regarding physiologic monitoring...

variability of tidal volume and respiratory rate in normally breathing man has long been demonstrated [1]. however because of lack of knowledge and technology primary ventilators could only deliver a fixed tidal volume in a fixed rate the so called volume controlled ventilation (vcv). vcv was volume preset time triggered and cycled and there was no synchronization with patient’s breaths. at tha...