Dermatofibroma (DF) is a very common benign skin tumor composed of fibroblasts, histiocytes, capillaries and collagen with multiple clinical presentations histological variants [1]. DF usually affects female patients at any age between 10 75 years old [2-4]. Most the time it presents as single, firm papular lesion slightly keratotic surface, sometimes brown pigmented or tone, frequently present...

LEOPARD syndrome is an autosomal dominant hereditary disease, which is characterized with cutaneous pigmented patches, electrocardiographic changes, ocular hypertelorism, retarded growth, pulmonic stenosis, genital abnormalities and congenital deafness. The gene of this disease have high penetrance but expression is varied and incomplete forms may be seen. We report a 23 year-old woman wi...

Larvae of Neenchelys Bamber are rather short and deep bodied, reaching about 75 mm before metamorphosis. They have a relatively short gut which is pigmented and slightly swollen at intervals along its length, as in larvae of other myrophine ophichthids. Neenchelys leptocephali also have a conspicuous midlateral patch of pigment about midway between the anus and caudal tip, and develop ova befor...

Hobnail hemangioma is a rare benign vascular tumor. It usually develops in young adults as a single, small, well-circumscribed, angiomatous/pigmented, and flat or exophytic lesion and has a distinctive biphasic histopathologic appearance. Lesions commonly affect the trunk and lower and upper extremities, although head and neck involvement has also been described. Until now, only 3 intraoral cas...

In Pleuronectiformes, blind-side malpigmentation (hypermelanosis) is common in cultured flatfishes, and is economically important. To understand the mechanism of blind-side hypermelanosis in flatfishes, we examined when the malpigmentation initially occurred, and studied how the symptoms proceeded during early development of the starry flounder, Platichthys stellatus. To assess quantitative pat...

introcduction: pigmented villonodular synovitis (pvs) is rare, benign and proliferative disorder of synovium which consists of villous and/ or nodular formations in joints.diagnosis is determined by clinical features, aspiration of the joint, radiographic features and magnetic resonance imaging (mri).the definitive treatment is the complete resection of affected tissue by open or arthroscopic s...

clinical and histopathological features of basal cell carcinoma (bcc) may differ according to the type of carcinogen involved. bcc arising from radiotherapy treatment has high incidence and its clinical and histopathological features may be different from bccs caused by other carcinogens. the aim of our study was to investigate any possible association between specific histopathological or clin...

VOLUME 97, MAY 2016 E1 WWW.CUTIS.COM To the Editor: Dermatofibroma is a common cutaneous lesion that most frequently affects young or middle-aged adults, especially women.1 Clinically, it appears as a firm, pink or brown nodule. It may be painful or show a tendency for scarring. The pathognomonic feature of dermatofibroma, regarded as a fibrohistiocytic tumor, is the so-called button sign cause...

BACKGROUND Erythema dyschromicum perstans (EDP)/Ashy dermatosis (AD), Lichen planus pigmentosus (LPP) and Pigmented contact dermatitis (PCD) are common skin diseases featuring abnormal pigmentation which have overlapping clinical features. OBJECTIVE To search for differences in the natural history, clinical features, histopathology and relevant contact allergens in patients those were clinica...