BACKGROUND Pituitary carcinoma is a rare entity requiring the presence of metastasis to confirm its malignant potential. We report a case of pituitary carcinoma and discuss the diagnosis and management of this lesion in relation to the existing literature. CASE PRESENTATION The patient is a 51-year-old woman with Cushing's disease and intact adrenal glands who was diagnosed with metastatic pi...

Apoplexy in sellar metastasis is very rare with only a few case reports in literature. A case of apoplexy in sellar metastasis from follicular thyroid carcinoma is reported and the literature is briefly reviewed. The patient presented with sudden onset headache and bi-lateral loss of vision following thyroidectomy in a case of follicular carcinoma thyroid with proven sellar metastasis. CT scan ...

Pituitary carcinomas are defined as pituitary tumors with craniospinal and/or systemic metastasis. These are rare and highly aggressive lesions. We present an unusual case of a 52-year-old male who had a pituitary adenoma removed via craniotomy. The tumor recurred three years post-op near the surgical tract, and slowly enlarged before removal two years later. Technically, this lesion was define...

Pituitary metastases are rare and metastatic pituitary lesions secondary of renal carcinoma are extremely rare. These lesions can be mistaken for pituitary adenomas and diagnosis can be very difficult. We report a 67-year-old Italian female complained of headache and visual impairment resulting from a sellar lesion with suprasellar extension. A transsphenoidal biopsy was performed and histologi...

The management of pituitary adenomas entails a multidisciplinary approach that involves neurosurgeons, endocrinologists, and radiation oncologists. Traditionally, the treatment included medical management, surgery (transsphenoidal microsurgical resection and transcranial approaches), and conventional fractionated radiotherapy. Stereotactic radiosurgery, through the various competing radiosurgic...

Tumors that metastasize to the pituitary gland are unusual, and are typically seen in elderly patients with diffuse malignant disease. The most common metastases to the pituitary are from primary breast and lung cancers. We report a 65-year-old woman with pituitary metastasis from breast cancer who presented with recent-onset left progressive deterioration of visual acuity and visual field. The...

The small pituitary mass was incidentally found in 40-years-old women with renal cell carcinoma. The endocrinological and ophthalmological evaluation revealed no deficit and the short-term follow-up was recommended. In 6 months later, the visual disturbance was reported and the size of mass was increased. The tumor was removed totally via the trans-sphenoid approach. The post-operative endocrin...

Metastatic tumors of the pituitary gland are not commonly diagnosed during life in cancer patients. The occurrence of symptomatic lesions is also very unusual and difficult to differentiate clinically and radiologically from pituitary adenomas. We report a case of pituitary metastasis which was the prime manifestation of a small cell lung carcinoma in a 40-year-old man. This cancer was revealed...

Pituitary adenomas are classified as typical or atypical, invasive or noninvasive, and aggressive or nonaggressive based on pathological features, radiological findings, and clinical behavior. Only pituitary tumors with cerebrospinal and/or systemic metastasis are considered malignant carcinomas. However, some pituitary adenomas with high Ki-67 indexes exhibit aggressive behaviors, such as rapi...