Expression of class II transactivator (CIITA), the transcriptional regulator that controls all class II expression, is controlled in cell lines in vitro by three promoters: the dendritic cell promoter PI, the B cell promoter PIII, and the interferon-gamma (IFN-gamma)-inducible promoter, PIV. The authors examined the promoter usage in vivo in mouse kidney in the basal state and in response to IF...

Major histocompatibility complex class II (MHCII) expression is regulated by the transcriptional coactivator CIITA. Positive selection of CD4(+) T cells is abrogated in mice lacking one of the promoters (pIV) of the Mhc2ta gene. This is entirely due to the absence of MHCII expression in thymic epithelia, as demonstrated by bone marrow transfer experiments between wild-type and pIV(-/-) mice. Me...

Major histocompatibility complex class II (MHCII) expression is regulated by the transcriptional coactivator CIITA. Positive selection of CD4 T cells is abrogated in mice lacking one of the promoters (pIV) of the Mhc2ta gene. This is entirely due to the absence of MHCII expression in thymic epithelia, as demonstrated by bone marrow transfer experiments between wild-type and pIV / mice. Medullar...

The universal character is a generalization of the Schur polynomial attached to a pair of partitions; see [8]. We prove that the universal character solves the Darboux chain. The N -periodic closing of the chain is equivalent to the Painlevé equation of type A N−1. Consequently we obtain an expression of rational solutions of the Painlevé equations in terms of the universal characters. Introduc...

Table 1: Parameters of PIV Circuit Particle image velocimetry (PIV) is used in experimental fluid dynamics to obtain a detailed localized view of velocity vectors in an unsteady fluid flow. In a nutshell, the estimated velocity field is computed from local correlations of snapshot-pairs of the particle-seeded flow, obtained by high-speed cameras [1-2]. PIV is used in a wide range of fields incl...

An experimental methodology is proposed for the study of aeroelastic systems. The approach locally evaluates forces involved in Collar’s triangle, namely aerodynamic, elastic, and inertial forces. position flow tracers as well markers on object surface monitored by a volumetric PIV system. From recorded images, surfare are separated based their optical characteristics. resulting images then ana...

It has been reported that sigma receptors are highly expressed in a variety of human tumors. In this study, we selected (+)-2-[4-(4-iodophenyl)piperidino] cyclohexanol [(+)-pIV] as a sigma receptor ligand and evaluated the potential of radioiodinated (+)-pIV for tumor imaging and therapy. (+)-[(125/131)I]pIV was prepared by an iododestannylation reaction under no-carrier-added conditions with r...

Mixing Co(NO3)2·6H2O/Dy(NO3)3·6H2O/(E)-4-(2-hydroxy-3-methoxybenzylideneamino)-2,3-dimethyl-1-phenyl-1,2-dihydropyrazol-5-one (HL)/pivalic acid/Et3N in various solvents results in the synthesis of seven compounds formulated as [CoII2DyIII2(μ3-MeO)2(L)2(piv)4(NO3)2] (3), [CoIIDyIII3(μ3-MeO)2(μ2-MeO)2(L)2(piv)2(NO3)3]·2(CH3OH) (4·2CH3OH), 2[CoII4DyIII4(μ2-O)2(μ3-OH)4(L)4(piv)8][CoII2DyIII5(μ3-OH)...

Mixing Co(NO3)2·6H2O/Dy(NO3)3·6H2O/(E)-4-(2-hydroxy-3-methoxybenzylideneamino)-2,3-dimethyl-1phenyl-1,2-dihydropyrazol-5-one (HL)/pivalic acid/Et3N in various solvents results in the synthesis of seven compounds formulated as [Co 2Dy III 2 (μ3-MeO)2(L)2(piv)4(NO3)2] (3), [Co Dy 3 (μ3-MeO)2(μ2MeO)2(L)2(piv)2(NO3)3]·2(CH3OH) (4·2CH3OH), 2[Co II 4Dy III 4 (μ2-O)2(μ3-OH)4(L)4(piv)8][Co II 2Dy III 5...

Parainfluenza virus (PIV) infections may be significant causes of morbidity and mortality in patients undergoing stem cell transplantation, but data regarding their impact on transplant-related mortality is limited. This study sought to determine the risk factors of PIV acquisition and progression to lower respiratory tract infection, their impact on transplant-related mortality, and the effect...