نتایج جستجو برای: plague
تعداد نتایج: 13533 فیلتر نتایج به سال:
Immune heterogeneity in wild host populations indicates that disease-mediated selection is common in nature. However, the underlying dynamic feedbacks involving the ecology of disease transmission, evolutionary processes, and their interaction with environmental drivers have proven challenging to characterize. Plague presents an optimal system for interrogating such couplings: Yersinia pestis t...
BACKGROUND Plague is a rapidly progressing, serious illness in humans that is likely to be fatal if not treated. It remains a public health threat, especially in sub-Saharan Africa. In spite of plague's highly focal nature, a thorough ecological understanding of the general distribution pattern of plague across sub-Saharan Africa has not been established to date. In this study, we used human pl...
Plague is a highly virulent fleaborne zoonosis that occurs throughout many parts of the world; most suspected human cases are reported from resource-poor settings in sub-Saharan Africa. During 2008-2016, a combination of active surveillance and laboratory testing in the plague-endemic West Nile region of Uganda yielded 255 suspected human plague cases; approximately one third were laboratory co...
Exposure to cats infected with Yersinia pestis is a recently recognized risk for human plague in the US. Twenty-three cases of cat-associated human plague (5 of which were fatal) occurred in 8 western states from 1977 through 1998, which represent 7.7% of the total 297 cases reported in that period. Bites, scratches, or other contact with infectious materials while handling infected cats result...
BACKGROUND No efficient vaccine against plague is currently available. We previously showed that a genetically attenuated Yersinia pseudotuberculosis producing the Yersinia pestis F1 antigen was an efficient live oral vaccine against pneumonic plague. This candidate vaccine however failed to confer full protection against bubonic plague and did not produce F1 stably. METHODOLOGY/PRINCIPAL FIN...
THE story of the Plague of Marseilles in I720-I has been vividly described by Gaffarel and Duranty2 and the part played by the administration, the faculty of medicine, the Church, the port officials and other public bodies has been carefully and sympathetically assessed. There are, however, many aspects of this epidemic which deserve further consideration. One is the research of Professor Anton...
3,510 ; 36 attacks and 23 deaths occurred there. I may note here that the speedy termination of the plague epidemic at Pachamba was principally due to the activity of the vigilance committee formed there, which induced generally the plague-infected families to depart from the town at the shortest notice. Though the plan was good for Pachamba, it probably helped to a certain extent the spread of...
Plague (Yersinia pestis infection) is a highly virulent rodent disease that persists in many natural ecosystems. The black rat (Rattus rattus) is the main host involved in the plague focus of the central highlands of Madagascar. Black rat populations from this area are highly resistant to plague, whereas those from areas in which the disease is absent (low altitude zones of Madagascar) are susc...
Outbreaks of plague in wildlife are sporadic and spatially dispersed, and they depend on coincidence of susceptible hosts, flea vectors, the plague bacterium (Yersinia pestis), and environmental factors that support pathogen transmission. We fit spatial models of plague outbreaks to a long-term data set (1981–2005) of towns of black-tailed prairie dogs (Cynomys ludovicianus) on the shortgrass s...
BACKGROUND Although the linkage between climate change and plague transmission has been proposed in previous studies, the dominant approach has been to address the linkage with traditional statistical methods, while the possible non-linearity, non-stationarity and low frequency domain of the linkage has not been fully considered. We seek to address the above issue by investigating plague transm...
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