In manufacturing, thermal spray technology encompasses a group of coating processes that provide functional surfaces to improve the performance of the components and protect them from corrosion, wear, heat and other failings. Many types and forms of feedstock can be thermal sprayed, and each requires different process conditions and life cycle preparations. The required thermal energy is genera...

The aim of this article was to study the trans-epithelial absorption to reach the blood and to target the brain by axonal transport using nasal formulations with nanonized meloxicam (nano MEL spray) and its salt form known as meloxicam potassium monohydrate (MELP spray). The physicochemical properties and the mucoadhesivity of nasal formulations were controlled. In vitro and in vivo studies wer...

Solution Precursor Plasma Spray (SPPS) technique is an emergent technique which offers significant performance advantages with various functional coatings like YSZ, ZnFe2O4, LSM, metal-doped ZnO, etc. Apart from the above capabilities, efforts towards development of an innovative hybrid approach through simultaneous deposition of powder and solution resulted in coatings with unique microstructu...

Thermal sprayed surface coatings are extensively used for a wide range of industrial applications. In the plasma spray process used in thermal spraying, the temperature of substrate and conduction of heat along the thickness of ceramic oxide coatings (TCOC) play an important role in the bond strength and microstructure of the coatings, which decides its performance and quality. In this study, u...

The removal of biofilms from microstructured titanium used for dental implants is a still unresolved challenge. This experimental study investigated disinfection and removal of in situ formed biofilms from microstructured titanium using cold atmospheric plasma in combination with air/water spray. Titanium discs (roughness (Ra): 1.96 µm) were exposed to human oral cavities for 24 and 72 hours (n...

The pharmacokinetics of spray dried composition (1:1 PAL: K12) and pure PAL was evaluated following oral administration (0.8 mg/kg) in healthy female Sprague Dawley rats. The extent of the mean plasma exposures of PAL was 11-fold higher in animals treated with spray dried mixture of PAL, K12 (1:1) compared to animals treated with PAL. Spray drying of PAL with Plasdones, especially Plasdone K12,...

Plasma concentrations of lignocaine were measured in three groups of anaesthetized patients following spraying of the trachea and larynx with a lignocaine 10% aerosol spray. Greater venous plasma concentrations occurred in patients who were paralysed with suxamethonium. A mean plasma concentration of 0.1 mug/ml of lignocaine resulted from each 10 mg of lignocaine used in spontaneously breathing...

Conventional and nanostructured YSZ coatings were deposited on the IN-738 Ni super alloy by the atmospheric plasma spray technique. The oxidation was measured at 1100°C in an atmospheric electrical furnace. According to the experimental results the nanostructured coatings showed a better oxidation resistance than the conventional ones. The improved oxidation resistance of the nanocoating could ...