Solitary plasmacytoma of the skull is rare and few cases have been reported in the English literature. Plasmacytoma of the skull has a wide spectrum of pathology, including a quite benign, solitary plasmacytoma (SPC), and an extremely malignant, multiple myeloma (MM) at the two ends of the spectrum. The prognosis for solitary plasmacytoma of the skull appears to be good when it can be diagnosed...

nant tumor composed entirely of plasma cells in the absence of bone involvement. These tumors can occur anywhere in soft tissue, especially in the upper respiratory tract and oral cavity (1). Plasmacytoma of the breast is a rare condition that may occur as a solitary finding or in association with multiple myeloma (2). We report here on a case of plasmacytoma of the breast that was associated w...

Plasmacytoma is a localized collection of malignant plasma cells. The disease is divided into Solitary plasmacytoma of the bone (SPB) and extramedullary plasmacytoma (EMP) which are both distinct entity. SPB usually occur in the bones characteristically affected in multiple myeloma and EMP was most frequently located in the oronasopharynx and paranasal sinuses, with a 15-30% incidence of region...

Solitary plasmacytoma is a rare disease characterized by a localized proliferation of neoplastic monoclonal plasma cells, without evidence of systemic disease. It can be subdivided into solitary bone plasmacytoma if the lesion originates in bone, or solitary extramedullary plasmacytoma if the lesion involves a soft tissue. The incidence of solitary bone plasmacytoma is higher than solitary extr...

the incidence of extramedullary plasmacytoma is 5% of all plasma-cell neoplasms. The vast majority of extramedullary plasmacytomas present as a tumor secondary to systemic myelomatosis of the bone marrow; extramedullary plasmacytoma involving the pancreas is very rare, and only 19 cases have been reported in the English-language literature (1). A few such reports have described the radiologic f...

Solitary plasmacytoma (SP), histologically indistinguishable from multiple myeloma (MM), is a kind of malignant tumor characterized by the proliferation of monoclonal plasma cells. SP is an independent subtype of plasmacytoma, including extramedullary plasmacytoma and solitary plasmacytoma of bone (SPB) [1]. Most solitary plasmacytomas progress to MM, and are usually treated in the department o...

1. Maskin LP, Diaz MF, Hlavnicka A, et al. Gastrointestinal bleeding secondary to multiple gastric plasmacytoma. Am J Clin Oncol 2008; 31: 100-1. 2. Chim CS, Wong WM, Nicholis J, et al. Hemorrhagic gastric plasmacytoma as the primary presentation in multiple myeloma. J Clin Oncol 2002; 20: 344-7. 3. Hamilton JW, McCluggage WG, Jones F, et al. Extramedullary gastric plasmacytoma. Ulster Med J 19...

Extramedullary plasmacytoma is rare in patients with diagnosed multiple myeloma. Soft tissue plasmacytoma of the gallbladder is particularly uncommon and has been described in only a handful of cases. Diagnosis of gallbladder plasmacytoma with fluorine 18-fluorodeoxyglucose (F18-FDG) positron emission tomography/computed tomography (PET/CT) has not previously been reported. We present a 65-year...

Extramedullary plasmacytoma (EMP) and solitary bone plasmacytoma (SBP) represent a disease continuum through a multistage process of cell differentiation, survival, proliferation, and dissemination, strictly related to multiple myeloma (MM), the second most common hematological malignancy. Herein, we report two cases of recurrent oral plasmacytoma progressed to MM, in which the first clinical s...

BACKGROUND AND AIM Long noncoding RNA-plasmacytoma variant translocation 1 is identified to be highly expressed and exhibits oncogenic activity in a variety of human malignancies, including pancreatic cancer. However, little is known about the overall biological role and mechanism of plasmacytoma variant translocation 1 in pancreatic cancer so far. In this study, we investigated the effect of p...