Abstract* Introduction: Chronic morphine exposure can cause addiction and affect synaptic plasticity, but the underlying neural mechanisms of this phenomenon remain unknown. Herein we used electrophysiologic approaches in hippocampal CA1 area to examine the effect of chronic morphine administration on short-term plasticity. Methods: Experiments were carried out on hippocampal slices taken f...

expansive behavior is usually observed in soils, which contain fractions of clay minerals in their composition. water absorption of clay particles and change of natural water content of soil up to plastic limit and down to shrinkage limit will cause significant volume change in expansive soils and will result in severe damages to the structures, buildings and foundations. swelling potential is ...

one of the new research fields in plasticity is related to choosing a proper non-associated flow rule (nafr), instead of the associated one (afr), to predict the experimental results more accurately. the idea of the current research is derived from combining von mises and tresca criteria in the places of yield and plastic potential surfaces in rate-independent plasticity.  this idea is implemen...

a semi-micromechanical multilaminate model is introduced here to predict the mechanical behavior of soils. this model is like a bridge between micro and macro scale upon the satisfaction of minimum potential energy level during any applied stress/strain increments. the concept of this model is based on a certain number of sampling planes which constitute the elastic-plastic behavior of the soil...

Introduction: The effects of cannabinoids (CBs) on synaptic plasticity of hippocampal dentate gyrus neurons have been shown in numerous studies. However, the effect of repeated exposure to cannabinoids on hippocampal function is not fully understood. In this study, using field potential recording, we investigated the effect of repeated administration of the nonselective CB receptor agonist WIN5...

micropolar plasticity provides the capability to carry out post-failure simulations of geo-structures due to microstructural considerations and embedded length scale in its formulation. an essential part of the numerical implementation of a micropolar plasticity model is the integration of the rate constitutive equations. efficiency and robustness of the implementation hinge on the type of inte...

In this paper the derivation of the second differentiation of a general yield surface implicit time stepping method along with its consistent elastic-plastic modulus is studied. Moreover, the explicit, trapezoidal implicit and fully implicit time stepping schemes are compared in rate-dependant plasticity. It is shown that implementing fully implicit time stepping scheme in rate-dependant plasti...

Clayey soils are the most common material used for water sealing and undertake an important role in controlling landfill-related pollution. Organic liquids can adversely affect the effectiveness of clay liners by drastically increasing their hydraulic conductivity. The aim of this study is to investigate and compare the permeability in two types of clay with different plasticity, exposed to the...