A technique-:was developed to facilitate creating computer-based instruction (CBI) with a Minimum of effort On the part of the-author/coder, and 'the feasibility of using a structure which puts control of the lesson strategy into the hands of the_student learner was investigated. A model which relieve* tire author' of CBI strategy selection was developed for the PLATO IV sySted and was testedin...

It has been nearly twenty years since the publication of P.Oxy. 2737, and the interpretation of lines 44-51 in particular still remains in dispute. These lines are especially vexing because they touch upon a wide range of issues, among them the early career of Plato Comicus and aspects of dramatic competition in fifth-century Athens. Four articles concerned with these lines have appeared in thi...

The PLATO trial revealed excess all-cause (4.5%) and vascular (4.0%) mortality after experimental pyrimidine, ticagrelor, and even higher death rates (5.9% and 5.1%, respectively) after clopidogrel, which have never been seen in any previous acute coronary syndrome (ACS) trial. The Food and Drug Administration (FDA) conducted, and recently released the ticagrelor review outlining some paradoxic...

Historically, most mathematicians have believed that mathematical truths such as "2+5=7" exist independently of human minds, being universally and eternally true. Mathematicians believe they are discovering properties of, say, prime numbers, rather than merely inventing them. This view of mathematics dates back to Pythagoras (500 BC) and Plato (400 BC). It is often called “Platonism”. In order ...

The methods to detect gene-gene interactions between variants in genome-wide association study (GWAS) datasets have not been well developed thus far. PLATO, the Platform for the Analysis, Translation and Organization of large-scale data, is a filter-based method bringing together many analytical methods simultaneously in an effort to solve this problem. PLATO filters a large, genomic dataset do...

Plato uses the idea of divinatory knowledge as a metaphorical descriptor for a variety of kinds of daytime, waking knowing. What unites these examples is that they all include discussion of a kind of knowing that cannot account for itself, and that is tentative, imagistic and non-discursive. These metaphorical uses can further be illuminated by his more detailed discussion of divinatory knowled...

This pape~ describes an "intelligent" tutor of foreign language concepts and skills based upon state-of-the-art research in Intelligent reaching Systems and Computational Linguistics. The tutor is part of a large R&D project in ITS which resulted in a system (called DART~ for the design and development of intelligent teaching dialogues on PLATO I and in a program (called ELISA~ for teaching for...