Introduction Pleomorphic adenoma, also known as mixed tumor, is the most common benign tumor of the major and minor salivary glands. The occurrence of pleomorphic adenoma of the tongue base is very rare, and very few cases have been reported in the literature. Objective The authors present a rare case of pleomorphic adenoma of the tongue base and a review of the literature. Case Report A 55-yea...

introduction: pleomorphic adenoma is a rare benign salivary gland neoplasm in children, which can be treated by simple excision. this tumor is rarely included in the differential diagnosis of solid submandibular masses in children. in the neonates, congenital pleomorphic adenoma usually presents in the nasopharynx. surgical excision is the treatment of choice and recurrence is not expected. we ...

introduction: pleomorphic adenomas are tumors mostly originating from salivary glands. these lesions in the larynx are very rare. case report: we report a rare case of pleomorphic adenoma that originated from the mucosal lining, just above the glottic area at the level of the laryngeal ventricle in a 55-year-old female patient. the tumor could not be palpated easily but was observed in the ct s...

Pleomorphic adenoma occurs commonly in the major salivary glands but is uncommonly encountered in the breast. In both of these locations, the tumor is typically grossly circumscribed and has a "mixed" histological appearance, being composed of myoepithelial and epithelial components amid a myxochondroid matrix. Herein, we report a case of pleomorphic adenoma of the breast which was preoperative...

BACKGROUND Pleomorphic adenoma (benign mixed tumor) is one of the most common salivary gland tumors. However, the processes involved in its carcinogenesis are not well defined. This study aimed to define the contribution of Nfr2 (nuclear factor (erythroid-derived 2)-like 2) to pleomorphic adenoma pathology. The Nrf2-controlled gene system is one of the most critical cytoprotective mechanisms, p...

a rare case of squamous cell carcinoma ex pleomorphic adenoma in maxillary sinus is presented. the patient is a 50-year-old woman presenting with a slow-progressive swelling in left side of her face that she has noticed 2 years earlier. the lesion was not painful and caused asymmetry and mild exophthalmos. microscopic examination revealed that the tumor was composed of two components partly of ...

OBJECTIVE: To report a case of pleomorphic adenoma that was surgically removed and to describe the surgical technique available remove this lesion. CASE REPORT: A male patient, caucasian, 46 years old, with 4-year history adenoma. He mentioned he went other services for treatment, but without success. came at our service treatment tumoral excision. Local anesthesia performed mepivacaine vasocon...

background and aims. various morphologies are seen in different salivary gland tumorsor within an individual tumor, and the lesions show divers biological behaviors. experimental results support the hypothesis that increased crkii proto-oncogene is associated with cytokine-induced tumor initiation and progression by altering cell motility signaling pathway. the aim of this study was to assess t...

Pleomorphic adenoma is the most prevalent salivary tumor, 65% of which occur in major glands. This tumor varies in terms of size depending on the gland where it is located. The most common sites of the minor salivary glands are the palate, lips, cheeks, and throat. Palatal pleomorphic adenoma is laterally located, rarely crossing the midline. This tumor is painless with slow growth rate, which ...

The objective of this review study was to encompass the relevant literature and current best practice options for this challenging, sometimes incurable problem. The source of the data was Ovid MEDLINE from 1946 to 2014. Review methods consisted of articles with clinical correlates. The most important cause of recurrence is enucleation with rupture and incomplete tumor excision at operation. Inc...