Phase locked loop (PLL) is one of the most critical devices in modern electronic systems. PLLs are widely used as clock generator or frequency synthesis in communication systems, computers, radio and other electronic applications. Phase noise represents the phase variations of a PLL output signal and is the most important characteristic of PLLs because it reflects the stability of PLL systems. ...

Poly-L-lysine (PLL) is commonly used as an adhibiting agent due to its good viscosity, and demineralized bone matrix (DBM) is a common enriched matrix for selective cell retention technology. Therefore, the aim of this study was to use PLL to coat the surface and interspaces of DBM to form a novel type of enriched matrix [DBM coated with PLL (PLL-DBM)], in order to effectively improve the enric...

This paper investigates the design and performance of the PLL (Phase Locked Loop). The proposed PLL designed with PFD (Phase Frequency Detector), CP (Charge Pump), first order Low Pass Filter and CS-VCO (Current Starved-Voltage Control Oscillator), in this paper the designed PFD used for proposed PLL is free from dead zone. The VCO used for the designed PLL shows larger tuning range and high ga...

We report a single-loop PLL that operates in a wide-bandwidth, fractional-N mode (with no fractional spur reduction scheme) during transient but in a narrow-bandwidth, integer-N mode during phase lock. This hybrid PLL, as an extension of the conventional fast-lock PLL (that shifts only its bandwidth while retaining the same frequency division mode), simultaneously achieves the fastlock advantag...

About 30 to 40 % of random bred Hartley strain (1) and all strain 2 guinea pigs (2) recognize hapten-poly-I.-lysine conjugates (H-PLL) as antigens. Strain 13 guinea pigs (2), mice, rats, and rabbits (3) do not make an immune response to these compounds. The immune response of guinea pigs to H-PLL conjugates has been shown to" be controlled by a dominant autosomal gene (2, 4). Contrasting with t...

Poly-lysine has been studied as a carrier for the delivery of drugs and nucleic acids for at least a decade. It is an especially attractive carrier for DNA and RNA, because of its condensed cationic charges. In our previous study, we showed that poly(ethylene glycol) (PEG) grafted to poly-L-lysine (PLL) remarkably increased the life time of a small interfering RNA (siRNA) in blood circulation. ...

AIM This study aimed to elucidate the pathogenesis of posterior longitudinal ligament (PLL) hypertrophy. METHODS Cervical PLL specimens were collected from CSM patients during surgery (n = 30) and during routine autopsy (n = 14), and processed for histological examination (HE staining and Masson's Trichrome staining) and IHC (CD3, CD68, CD31, TGF-β1 and collagen II). In addition, the mRNA exp...

Primary Lens Luxation (PLL) is an inherited disease common in Terrier breeds. A truncating mutation in the ADAMTS17 orthologue on CFA03 is reported to cause PLL in 17 breeds, mostly Terriers. This study investigated the mode of inheritance and penetrance of PLL, age of the ADAMTS17 mutation, and other possible causes of PLL in Australian Tenterfield Terriers and Miniature Bull Terriers. The ADA...

Gold nanoparticle-coated Pluronic-b-poly(L-lysine) nanoparticles (Pluronic-PLL@Au NPs) were synthesized via an easy one-step method and employed as carriers for the delivery of paclitaxel (PTX) in chemo-photothermal therapy, in which Pluronic-PLL acts as the reductant for the formation of AuNPs without the need for an additional reducing agent. METHODS The deposition of AuNPs on the surface o...

Folate-polymer-coated liposomes were developed for targeted chemotherapy using doxorubicin (DXR) as a model drug. Folate-poly(L-lysine) (F-PLL) conjugates with a folate modification degree of 16.7 mol% on epsilon amino groups of PLL were synthesized. DXR-loaded anionic liposomes were coated with F-PLL, and the cellular association of F-PLL-coated liposomes was evaluated by flow cytometry, and c...