Discrete fluid volumes (plugs) are often needed for micro bioassay. Current methods of isolating discrete volumes use electrokinetic forces that require high voltages and result in ionic component separation of the sample. Pressure-driven flow through a double-T metering junction is a suggested alternative to this electrokinetic method. There has been no extensive analysis of pressure-driven pl...

To improve the calculation of the flow properties of an aerospike nozzle, different turbulence models were investigated in this study. The primary shape of the nozzle plug is determined through utilizing an approximate method. The flow field is, then, simulated using the Navier-Stokes equations for compressible flows. The commercial computational fluid dynamics code Fluent is used to simulate t...

This paper is concerned with the study of the peristaltic flow of Herschel – Bulkley fluid in an inclined flexible channel lined with porous material under long wave length and low Reynolds number assumptions. This model may be applicable to describe blood flow in the sense that erythrocytes region and the plasma regions may be described as plug flow and non-plug flow regions. The effect of yie...

Flow-through polymerase chain reaction (PCR) microfluidic systems for fast, small-volume DNA amplification on a single chip are significantly impacting medical and bioanalytical research. We have fabricated an improved, practical flow-through PCR chip by weighting a pressure-sensitive polyolefin (PSP) film onto a cyclo-olefin polymer (COP) substrate. The substrate was cut so as to produce micro...

A numerical framework for modelling platelet plug dynamics is presented in this work. It consists of an extension of a biochemical and plug growth model with a solid mechanics model for the plug coupled with a fluid-structure interaction model for the blood flow-plug system. The platelet plug is treated as a neo-Hookean elastic solid, of which the implementation is based on an updated Lagrangia...

Microfluidic techniques are employed to investigate air-liquid flows in the lung. A network of microchannels with five generations is made and used as a simplified model of a section of the pulmonary airway tree. Liquid plugs are injected into the network and pushed by a flow of air; they divide at every bifurcation until they reach the exits of the network. A resistance, associated with the pr...

Objective- Obtaining the normal images ofcolor doppler and estimation ofblood flow velocity parametersof femoral and axillary arteries in dog.Design- Descriptive studyAnimals- 7 healthy adult mixed-breed dogs, weighing 14.3 ± 2.8 kg (mean ± SD).Proceudure- Left and right femoral and axillary arteries of hind and forelimbs were evaluated. Colorand spectral doppler images ofthe each artery were o...

The quest for the ever-greater operational flexibility of large-scale steam turbines continues to drive enhanced control valve design. Such components, subjected to large static loads, also may experience strong vibrations due to unsteady turbulent fluctuations downstream of the throttling section. Challenging design efforts are required to ensure that these fluctuations are confined far from s...

In this study, we investigate the steady propagation of a liquid plug in a two-dimensional channel lined by a uniform, thin liquid film. The liquid contains soluble surfactant that can exist both in the bulk fluid and on the air-liquid interface. The Navier-Stokes equations with free-surface boundary conditions and the surfactant transport equations are solved using a finite volume numerical sc...