1. Strains of staphylococci produce diazotizable materials which can be converted to a dye, and the intensity of the color reaction can be quantitated in the same manner as p-aminobenzoic acid. The sulfonamide-resistant strains which we have studied produce more diazotizable substance than non-resistant strains. 2. The development of a color by the diazotizable substance can be inhibited by exp...

pteroic acid and dihydrofolic acid from p-aminobenzoic acid and p-aminobenzoylglutamic acid, respectively, in the presence of pyrophosphorylmethyldihydropteridine. In the enzymatic reaction, p-aminobenzoic acid was more active as substrate than p-amino benzoylglutamic acid. When p-aminobenzoic acid and L-glutamic acid were used in place of p-aminobenzoic acid in the enzyme system, dihydropteroi...

Using the substrate N-acetyl-L-tyrosyl-p-aminobenzoic acid, we determined chymotrypsin activity in the small intestine of calf, pig, and poultry. Orally administered N-acetyl-L-tyrosyl-p-aminobenzoic acid is enzymatically cleaved in vivo, and the released p-aminobenzoic acid is determined by HPLC. We found that the p-aminobenzoic acid concentration in plasma and urine was significantly influenc...

Para-Aminobenzoic acid is supported on silica gel via reaction of activated silica gel and p-aminobenzoic acid which is then converted to its manganese and cobalt salts. A mixture of the manganese and cobalt salts of the acid is used to catalyze allylic and benzylic alcohols to their corresponding carbonyl compounds in reasonable yields using oxygen or air. Reactions are clean and the catal...

para-aminobenzoic acid is supported on silica gel via reaction of activated silica gel and p-aminobenzoic acid which is then converted to its manganese and cobalt salts. a mixture of the manganese and cobalt salts of the acid is used to catalyze allylic and benzylic alcohols to their corresponding carbonyl compounds in reasonable yields using oxygen or air. reactions are clean and the catalysts...

Since the eshablishment of p-aminobenzoic acid as a member of the B vitamin group, a considerable interest has been shown in methods of determination in natural materials. Since known chemical methods are not sufficiently sensitive, it became evident that microbiological tests should be the most practicable. The organism Clostridium acetobutylicum has been used (I) but no general assay procedur...

The formation of folic acid compounds from pteridines and p-aminobenzoic acid by whole bacterial cells has been studied by Korte et al. (1, 2), who reported that C%xanthopterin (2-amino4,6-dihydroxypteridine) could be incorporated into folic acid by several bacterial species, and by Weygand et al. (3), who found that certain strains of bacteria can be adapted to utilize 2.amino-4-hydroxy-6-form...