BACKGROUND Metformin is effective for the treatment of polycystic ovary syndrome, but conflicting results regarding its effect on adipocytokine levels (adiponectin, resistin, visfatin, and leptin) in patients with polycystic ovary syndrome receiving metformin treatment have been reported. To provide high-quality evidence about the effect of metformin treatment on adipocytokines in patients with...

OBJECTIVE To compare lipid profile in lean and obese women with polycystic ovary syndrome with normal weight and obese controls. METHOD The case-control study was conducted at the Department of Chemical Pathology, Liaquat National Hospital, Karachi, from March 2006 to April 2007. It comprised 50 cases of polycystic ovary syndrome along with 50 healthy controls matching for age, gender and wei...

Women with polycystic ovary syndrome are characterized by obesity, menstruation irregularity, hirsutism and infertility, and prevalent with cardiometabolic comorbidities, but population-based studies on the risk of developing coronary artery disease are limited. From claims data of the Taiwan National Health Insurance, we identified 8048 women with polycystic ovary syndrome aged 15-49 years new...

abstract background: “polycystic ovary syndrome (pcos) is a complex endocrine and metabolic disorder associated with ovulatory dysfunction”. “autonomic and central nervous systems play important roles in the regulation of ovarian physiology”. the noradrenergic nucleus locus coeruleus (lc) plays a central role in the regulation of the sympathetic nervous system and synaptically connected to the ...

background: some studies propose that changes in leptin concentrations (above or under the normal range) result in infertility. therefore, we investigated serum and follicular fluid leptin concentrations in infertile women with polycystic ovary syndrome (pcos). objective: to study serum and follicular fluid leptin concentrations in infertile women with pcos. materials and methods: we conducted ...

objective: exercise activity could be an amendment to polycystic ovary syndrome (pcos). however the acute and chronic effects of various exercise intensities on serum leptin levels are ambiguous. this study investigates the acute and chronic responses of various intensities of exercise on serum leptin levels and weights of female rats with pcos. methods: in this semi-empirical study, 80 adult w...

Due to genetic heterogeneity and variable diagnostic criteria, genetic studies of polycystic ovary syndrome are particularly challenging. Furthermore, lack of sufficiently large cohorts limits the identification of susceptibility genes contributing to polycystic ovary syndrome. Here, we carried out a systematic search of studies deposited in the Gene Expression Omnibus database through August 3...

PURPOSE To evaluate the prevalence of common mental disorders in women diagnosed with polycystic ovary syndrome as compared with paired controls without this syndrome. METHODS Cross-sectional study with a Control Group examining women between the ages of 18 and 30 who did not use antidepressants and who sought the Gynecology Service of the researched sites. For every woman diagnosed with the ...