Monolayers of charged polystyrene latex particles ranging in size from 100 nm to 10 m were deposited on oppositely charged polyelectrolyte multilayers (PEMs) by electrostatic interactions and capillary forces. Ultrathin PEMs (∼30 nm) formed on a glass slide provided an e p i a l s c a ©

We demonstrate an approach to the assembly of DNA-containing polyelectrolyte multilayers that can be used to promote rapid release of DNA from surfaces. The approach is based on layer-by-layer incorporation of poly(acrylic acid) to promote rapid erosion in physiologically relevant media.

Natural polyelectrolyte multilayers of chitosan (CHI) and alginate (ALG) were alternately deposited on doxorubicin (DOX)-loaded poly (lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) with layer by layer self-assembly to control drug release for antitumor activity. Numerous factors which influenced the multilayer growth on nano-colloidal particles were studied: polyelectrolyte concentration, ...

We systematically investigate the effects of divalent anions on the assembly of polyelectrolyte multilayers by fabricating polystyrene sulfonate (PSS)/polyallylamine hydrochloride (PAH) multilayer films from aqueous solutions containing SO(4)(2-), HPO(4)(2-), or organic dicarboxylate dianions. The chosen concentrations of these anions (i.e., ≤0.05 M) allow us to isolate their effects on the ass...

Stable multilayer thin films, assembled by a combination of layer-by-layer processing of polyelectrolytes and inorganic quantum dot monolayers prepared using the Langmuir-Schaefer deposition procedure, have been examined. Film formation and structure are confirmed using UV-vis absorption measurements and fluorescence spectroscopy. Growth is shown to be linear over several polyelectrolyte-quantu...

We present a novel approach to probe elastic properties of polyelectrolyte multilayer microcapsules. The method is based on measurements of the capsule load-deformation curves with the atomic force microscope. The experiment suggests that at low applied load deformations of the capsule shell are elastic. Using elastic theory of membranes we relate force, deformation, elastic moduli, and charact...

The concept of splayed, hyperthin polyelectrolyte multilayers (PEMs) is introduced in which a bulky, hydrophilic and charged pendant group is used to increase the gas permeability of a PEM without reducing its permeation selectivity. Proof of principle studies are reported using nm-thick PEMs made from poly(sodium 4-styrene sulfonate) () and poly(allylamine hydrochloride) () bearing bulky cobal...

We present a novel approach for Layer-by-Layer (LbL) polyelectrolyte deposition in a “microfluidic pinball” device. Polyelectrolyte multilayers (PEMs) were coated on oil droplets by guiding them through parallel laminar streams of alternatively charged polyelectrolytes. Conventional LbL process is a time consuming and laborious process [1]. Past microfluidics based LbL approaches add operationa...