Nanotechnology is a promising approach both for restoring or enhancing activity of old and conventional antimicrobial agents and for treating intracellular infections by providing intracellular targeting and sustained release of drug inside infected cells. The present paper introduces a formulation study of gentamicin loaded biodegradable nanoparticles (Nps). Solid-oil-in water technique was st...

Protamine-oligonucleotide nanoparticles represent effective colloidal drug carriers for antisense phosphorothioate oligonucleotides (PTO). This study describes improvements in particle preparation and the physicochemical properties of the complexes prepared. The influence of component concentrations, length of the PTO chain and the PTO/protamine weight ratio on particle formation and size, shap...

The physiological and metabolic mechanisms behind the humic acid-mediated plant growth enhancement are discussed in detail. Experiments using cucumber (Cucumis sativus) plants show that the shoot growth enhancement caused by a structurally well-characterized humic acid with sedimentary origin is functionally associated with significant increases in abscisic acid (ABA) root concentration and roo...

Hyperthermia increases the efficiency of various chemotherapeutic drugs and is administered as an adjunct to chemotherapy for the treatment of cancer patients. The temperature-dependent effect can be strongly increased by the use of temperature-sensitive liposomes in combination with regional hyperthermia, which specifically releases the entrapped drug in the heated tumor tissue. The novel lipi...

BACKGROUND Formaldehyde (HCHO) is a gas (available as a 37% concentrated solution, stabilized with methanol). The 10% dilution (approximately 4% formaldehyde) has been used as a fixative since the end of the 19th century. Alternative fixatives are also commercially available or may be prepared in-house in laboratories. Statements by the IARC, along with other USA agencies (CalEPA, RoC/NTP) on t...

We have developed a bright, photostable, and far-red emitting fluorescent phosphoglycerolipid analogue to probe diffusion characteristics of lipids in membranes. The lipid analogue consists of a saturated (C18) phosphoethanolamine and a hydrophilic far-red emitting fluorescent dye (KK114) that is tethered to the head group by a long polyethylenglycol linker. In contrast to reported far-red emit...

in order to study, the effect of pre-cooling treatment, osmotic potential and water stress on some population of two species of satureja bachtiarica and satureja sahendica was studied by a factorial experiment based on completely randomized design with three replications in laboratory and greenhouse conditions during one year in the gene bank of institute of forests and range lands by the years...

seed dormancy is a temporary failure of a viable seed to germinate. various methods are used for breaking seed dormancy, depending on plant species and type of dormancy. three seed populations originated from esfahan, semnan and fars provinces were exposed to different seed dormancy breaking treatments such as mechanical and chemical scarification, humid chilling, ga3 and polyethylenglycol 6000...

       Food packaging extensively uses plastic films and containers of petroleum-based polymers for their excellent functional properties and competitive price. Plastic packaging has become a central focus of waste reduction efforts, particularly in aesthetic terms of damage to flora and fauna. Presently, consumers require greater quality and longer shelf lives for their foodstuffs, while they ...

drought resistance is a very important characteristic needed for plant survival especially at germination stage, in arid and semi-arid lands. phosphatase enzymes are widely found in plants. these enzymes are responsible for dephosphorylation of organic phosphate and altering it to mineral phosphate. germination experiments were conducted in two bread wheat cultivars (sardari and alvand) under s...