The advent of biocompatible and biodegradable scaffolds has opened up a plethora possibilities in neural tissue engineering. An emerging approach to overcome some existing drawbacks scaffold design functioning is natural conductive polymeric scaffold. It analogous the extracellular matrix provides an environment conducive growth. This study focuses on fabrication soft scaffold, reinforced with ...

Objective (s): Silicate bioceramics containing Zn and Ca like hardystonite (Hr) with chemical formula Ca2ZnSi2O7 has attracted the attention of researchers in biomedical field due to its remarkable biological and mechanical properties. The new generation of bioceramics can applied in bone tissue engineering to substitute with infected bone. However, these zirconium-silicate bioceramics have pro...

The aim of this study was to evaluate the bone regeneration of hydroxyapatite (HA)/alumina bilayered scaffold with a 3 mm passage-like medullary canal in a beagle tibia model. A porous HA/alumina scaffold was fabricated using a polymeric template-coating technique. HA/alumina scaffold dimensions were 10 mm in outer diameter, 20 mm in length, and with either a 3 mm passage or no passage. A 20 mm...

The use of biopolymers as a three dimensional (3D) support structure for cell growth is a leading tissue engineering approach in regenerative medicine. Achieving consistent cell seeding and uniform cell distribution throughout 3D scaffold culture in vitro is an ongoing challenge. Traditionally, 3D scaffolds are cultured within tissue culture plates to enable reproducible cell seeding and ease o...

Porous polymeric scaffolds have been much investigated and applied in the field of tissue engineering research. Poly(ester urethane) (PEU) scaffolds, comprising pores of 1-20  μ m in diameter on one surface and ≥ 200 μ m on the opposite surface and in bulk, were fabricated using phase separation method for hypopharyngeal tissue engineering. The scaffolds were grafted with silk fibroin (SF) gene...

In this study we aim to boost the functional output of the intra-kidney islet transplantation for diabetic patients using a tissue engineered polymeric scaffold. This highly porous electrospun scaffold featured randomly distributed fibers composed of polycaprolactone (PCL) and poliglecaprone (PGC). It successfully sustained murine islets in vitro for up to 4 weeks without detected cytotoxicity....

Atmospheric pressure non equilibrium plasma treatments have been implemented to produce solvent-free Poly-L-lactic acid (PLLA) scaffolds, to improve biocompatibility of PLLA mats and to increase electrolyte uptake of Poly(vinylidene fluoride) (PVDF) separators for lithium batteries. It has been observed that plasma treatments are a suitable way to improve polymeric solution electrospinnability,...

Purpose/Introduction Tissue engineering aims to regenerate new biological tissues in order to replace diseased or injured tissues. Polymeric scaffolds for cell seeding, cell growth and proliferation are often extremely sensitive to histological processing. Therefore 3D non-invasive and quantitative imaging methods are needed to study tissue-engineered constructs before and after implantation. T...

Polymeric scaffolds used in regenerative therapies are implanted in the damaged tissue and submitted to repeated loading cycles. In the case of articular cartilage engineering, an implanted scaffold is typically subjected to long-term dynamic compression. The evolution of the mechanical properties of the scaffold during bioresorption has been deeply studied in the past, but the possibility of f...