BACKGROUND AND PURPOSE There are limited studies on the morphologic characteristics of MCA atherosclerotic stenosis. Our aim was to quantitatively assess the remodeling pattern and plaque distribution of atherosclerotic MCAs with 3T high-resolution MR imaging. MATERIALS AND METHODS Eighty-seven consecutive patients with symptomatic atherosclerotic stenoses at the M1 segment of the MCA on DSA ...

micrornas participate in the regulation of asthma, the goal of this study is to summarize recent researches on the roles of micrornas in the pathogenesis of asthma. a review of the english medical literatures was conducted by searching pubmed for studies concerning asthma and micrornas. the results of the present study indicate that micrornas play important roles in regulating asthma immune res...

the widespread use of sulfur mustard  (sm) as a chemical warfare agent in the  past century has proved its long-lasting toxic effects. despite a lot of research over the past decades on iranian veterans, there are still major gaps in the sm literature. transforming growth  factor  (tgf-β),  a  cytokine  that  affects  many  different  cell processes,  has  an important role in the lungs of pati...

asthma is a chronic inflammatory disease of the airway with extensive airway remodeling. the ethical issues associated with the studies in asthmatic patients, required development of animal model of asthma. animal models of asthma can provide valuable information on several features of asthma pathogenesis and treatment. although these models cannot carry out all clinical features, they are valu...

OBJECTIVES The study was done to elucidate the relationship between baseline arterial remodeling and clinical outcome following stenting. BACKGROUND The impact of preintervention arterial remodeling on subsequent vessel response and clinical outcome has been reported following nonstent coronary interventions. However, in stented segments, the impact of preintervention remodeling on clinical o...

objective: asthma is an airway complex disease defined by reversible airway narrowing and obstruction, chronic airway inflammation, airway hyperresponsiveness, and tissue remodeling. the purpose of this study was to determine the effect of brassica napus l. (b. napus) on airway pathologic changes in a rat model of asthma. materials and methods: twenty-four rats were divided into 4 groups: contr...

Mechanosensitive osteocytes are essential for bone remodeling. Nitric oxide, an important regulator of bone remodeling, is produced by osteocytes through the activity of constitutive endothelial nitric oxide synthase (eNOS) or inducible nitric oxide synthase (iNOS). We hypothesized that these enzymes regulate the tissue response to orthodontic force, and therefore we investigated eNOS and iNOS ...

BACKGROUND AND PURPOSE Preliminary studies suggest that intracranial arteries are capable of accommodating plaque formation by remodeling. We sought to study the ability and extent of intracranial arteries to remodel using 3-dimensional high-resolution black blood magnetic resonance imaging and investigate its relation to ischemic events. METHODS Forty-two patients with cerebrovascular ischem...