نتایج جستجو برای: post translational modification

تعداد نتایج: 559087  

Journal: :Cell 2016
Julia Schaletzky Michael Rape

Posttranslational modifications control microtubule behavior, yet assigning roles to particular signals was hampered by lack of defined in vitro systems. In this issue of Cell, Valenstein and Roll-Mecak establish a biochemical platform to interrogate consequences of microtubule polyglutamylation, thereby providing important insights into the specificity and quantitative nature of cellular infor...

2008
Viroj Wiwanitkit

Post-translational modifications of proteins control many biological processes. This is also an important process in the pathogenesis of diabetes mellitus. Adiponectin is an insulin-sensitizing adipokine with antidiabetic, anti-atherogenic, anti-inflammatory and cardioprotective properties. The role of posttranslational modifications in regulating the biosynthesis of high molecular weight adipo...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2014
Ming-kun Yang Yao-hua Yang Zhuo Chen Jia Zhang Yan Lin Yan Wang Qian Xiong Tao Li Feng Ge Donald A Bryant Jin-dong Zhao

We describe an integrated workflow for proteogenomic analysis and global profiling of posttranslational modifications (PTMs) in prokaryotes and use the model cyanobacterium Synechococcus sp. PCC 7002 (hereafter Synechococcus 7002) as a test case. We found more than 20 different kinds of PTMs, and a holistic view of PTM events in this organism grown under different conditions was obtained withou...

Journal: :Acta Crystallographica Section D Biological Crystallography 2013

Journal: :Nature Reviews Molecular Cell Biology 2011

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