Enterobacter sakazakii represents a significant risk to the health of neonates. This bacterium is an emerging opportunistic pathogen that is associated with rare but life-threatening cases of meningitis, necrotizing enterocolitis, and sepsis in premature and full-term infants. Infants aged <28 days are considered to be most at risk. Feeding with powdered infant formula (PIF) has been epidemiolo...

On September 11,2008, FDA learned that melamine may be contained in an infant formula manufactured by a firm in China. As of September 21, 2008, FDA learned that a total of 52,857 cases of nephrolithiasis (and, in some instances, renal failure) had been reported in China linked to consumption of this contaminated powdered formula. There have been approximately 13,000 hospitalizations, and at le...

To the Editor: Enterobacter saka-zakii, a gram-negative rod-shaped bacterium, is an emerging foodborne pathogen that can cause meningitis, sepsis, or necrotizing enterocolitis in newborns, particularly affecting premature or other immunocompromised infants. Although an environmental reservoir and mode of transmission for E. sakazakii has not been clearly identified, a growing number of reports ...

A simple and rapid column-switching ion chromatography with non-suppressed conductivity detection method was developed for simultaneous determination of L-carnitine, choline and mineral ions (free sodium, potassium, magnesium and calcium ions) in milk and powdered infant formula samples. On-line sample clean-up was achieved on the pretreatment column Dionex IonPac NG1 (50 mm 4 mm, i.d.), with p...

Powdered infant formula is not sterile and may be intrinsically contaminated with pathogens, such as Salmonella enterica, that can cause serious illness in infants. In recent years, at least 6 outbreaks of Salmonella infection in infants that have been linked to the consumption of powdered infant formula have been reported. Many of these outbreaks were identified because the Salmonella strains ...

In April 2016, a female infant was born via Cesarean delivery at 29 estimated gestational weeks and had a birthweight of 3 pounds (1,405 grams). Her clinical course in the neonatal intensive care unit was unremarkable until she developed signs of sepsis at age 21 days. Cultures of blood and cerebrospinal fluid yielded Cronobacter sakazakii, a gram-negative pathogenic bacillus. Despite treatment...

OBJECTIVE Distribution of breast milk substitutes (BMS) after the 2006 Yogyakarta earthquake was uncontrolled and widespread. We assessed the magnitude of BMS distribution after the earthquake, its impact on feeding practices and the association between consumption of infant formula and diarrhoea among infants and young children. DESIGN One month after the earthquake, caregivers of 831 childr...

Abstract The toxicity and the health risk assessment associated to presence of some hazardous elements (HEs) in dried (infant formula powdered) milks due manufacturing packaging process, raw materials used, environmental conditions, etc. need be determined. With this aim, a new methodology based on combination quotients non-supervised (as cluster analysis (CA) principal component (PCA)) chemome...