Nucleolar organizer regions (Ag-NORs) were studied in patients with cervical precancerous and cancerous lesions along with controls. The data revealed a statistically significant decrease of Ag-NORs in cancer patients, as well as in women with severe precancerous lesions as compared with controls. A similar decrease in the amount of Ag-staining was also observed in both cancer and severe dyspla...

Cervical cancer is always preceded by epithelial lesions which have larger and more densely spaced nuclei than normal tissue. Detecting and removing these lesions prevents the development of cervical cancer. A proposed method to detect precancerous lesion in vivo is to use the nuclear size and density information from fiber optic confocal images of the cervical epithelial tissue to classify the...

OBJECTIVES We explore the clinical potential of reflectance and fluorescence confocal microscopy to image the morphologic and biochemical changes associated with precancer, in order to aid in the detection and diagnosis of cervical dysplasia. METHODS Cervical epithelial tissue samples imaged ex vivo or in vivo were obtained from M. D. Anderson Cancer Center and Lyndon B. Johnson Hospital in H...

Cervical cancer is a serious health problem and most of the cases occur in less developed countries where effective screening systems are lacking. The aim of our present study is to delineate the age for early detection of precancerous cervical lesions. Cervical smears were screened (Pap test) over a period of four and half years from January 2000 to June 2004. The pattern of lesions was found ...

Cervical cancer is the second most common female cancer in Thailand and worldwide (IARC, 2005; Ferlay et al., 2010). Persistence high risk HPV infection is known as a leading cause of cervical cancer (Schiffman and Kjaer, 2003; IARC, 2005). Most of the cervical cancer cases developed in the developing countries. Despite of the wide spreading of the disease, cervical cancer is one of the prevent...

The present review introduces the aetiology and classification of cervical precancers. principles diagnosis based on colposcopy are reviewed. indications for targeted biopsy steps in diagnostic process Prophylaxis these diseases prevents cancer as high-grade precancerous lesions represent a direct precursor to cancer. basics primary secondary prevention, types screening, behaviour already-alert...

Human papillomavirus (HPV)-related cancers remain one the most common causes of cancer-related mortality worldwide [1]. HIV-infected women are at even higher risk of cervical cancers compared with HIV-uninfected women, and HIV-infected men and women are at increased risk of anal cancer compared with their HIVuninfected counterparts [2–4]. HPV-associated cancers are largely preventable. Primary ...

Cervical cancer is the second most common cancer in women worldwide. There are about 60,000 newly detected cases and 30,000 deaths annually in Europe, with the highest incidence reported from Eastern Europe countries. According to data from the National Institute of Public Health, in Croatia the incidence of cervical cancer was 14.9/100,000 in 2006, ranking eighth most common malignancy in wome...

Cervical cancer is one of the major causes of women death worldwide. The aim of this study was to test the sensitivity and specificity of visual inspection with acetic acid (VIA) and visual inspection with lugol iodine (VILI) as a diagnostic test for cervical cancer in comparison with Pap smear in the North Cameroon region. 309 women aged between 20 to 62 years were recruited in this study. 307...