The objective of this study was to identify possible changes in mRNA and protein expression of high-mobility group box protein 1 (HMGB1) and its suggested receptors - receptor for advanced glycation end-products (RAGE) and Toll-like receptor 2 (TLR2) and TLR4 - in human cervix during pregnancy, term and preterm labor. Cervical biopsies were taken from 58 women: 20 at preterm labor, 24 at term l...

prematurity is the most common cause of neonatal death. risk factors of premature birth can be related with ethnicity and genetic. there is no comprehensive high sample size study in kurdish ethnicity to determine risk factors related to prematurity. this study evaluated risk factors of preterm labor in kurdish ethnicity.this case-control study was conducted in 200 preterm infants (case group) ...

OBJECTIVE Preterm labor is one of the common causes of prenatal morbidity and mortality. With considering the importance of preterm labor and lack of sufficient studies about the relationship between preterm labor and some factors such as cigarette smoking and opiate-using, the present study was designed. METHODS We performed this descriptive-analytic study on 988 pregnant women referring to ...

aim of this study is to determine the risk of adverse pregnancy outcome by maternal serum alpha-fetoprotein (msafp) level. we followed 295 pregnant women from msafp screening in the 14th to 22th week of gestation until the end of pregnancy and information on pregnancy outcome have been recorded in questionnaires. of 295 pregnant women, 270 had term labor and 25 had preterm labor. the frequencie...

background: spontaneous preterm labor is one of the common obstetrics problems causing several physical, psychological and economical outcomes. although due to these outcomes and the efficacy of cares for decreasing them, preterm labor screening is cost-effective and it is still one of the challenging issues in obstetrics. objective: in this study preterm labor screening by using cervical trans...

background : the measuring serum ferritin level as a sensitive inflammatory biomarker might effectively predict preterm delivery, but the power and the best cut-off point of this biomarker for predicting preterm labor in iranian population has not been substantially identified. our purpose was to determine what concentrations of serum ferritin could identify patients at risk for preterm deliver...

OBJECTIVE To describe expectant women's experiences with the onset of preterm labor. DESIGN Qualitative, using grounded theory methods. SETTING Southwestern tertiary women's hospital. PARTICIPANTS Thirty pregnant women who were less than 35 weeks gestation, had experienced preterm labor within the past 7 days, and had no previous experience with preterm labor. DATA SOURCE Taped and tran...

BACKGROUND This paper, the first of a two-part series on premature labor, reviews the recent literature on the causes of and risk factors for preterm labor and methods of diagnosis. METHODS A review of the literature on risk determination and diagnosis of preterm labor was conducted by searching MEDLINE files from 1983 to the present, using the key terms "preterm labor," "premature labor," "p...

at the present, many drugs are used for inhibition of uterine contractions, but the proportions of preterm labors are increasing. although magnesium sulfate is the most commonly prescribed parenteral tocolytic agent, but its optimal use has yet to be delineated. in this study a high-dose protocol for magnesium sulfate tocolytic therapy was compared with a low-dose regimen. one-hundred patients ...

Preterm labor is responsible for a majority of cases of perinatal morbidity and deaths. Prevention of preterm labor is not usually possible; thus pharmacologic treatment is the only recourse available. Numerous agents have been used to treat preterm labor, but none has proved to be superior. This report reviews the current information available about the pharmacology of labor-inhibiting drugs a...