Modern therapy has changed the way diseases are controlled and has brought significant benefits. In spite of all the benefits, adverse drug reactions are a common, often preventable, cause of illness, disability and even death. Besides the intrinsic danger associated with the drug, patients might have a particular, unpredictable hypersensitivity to certain drugs, which requires careful monitori...

severe adverse drug reactions are an important cause of childhood morbidity and mortality. despite this, few reports in the literature describe it. this study was designed to evaluate the admitted pediatric patients due to adverse drug reactions. this retrospective study was conducted at pediatric ward of besat hospital. the records of hospitalized patients that admitted with diagnosis of adver...

results: a total number of 117 patients were evaluated for adverse drug reactions, among them, 97 (82.9%) were considered to have immunological drug reactions. the most common symptoms of allergic drug reactions were morbilliform eruptions, serum sickness, dress (drug rash with eosinophilia and systemic symptoms), and toxic epidermal necrolysis. in 62 patients, anticonvulsant drugs had the prom...

BACKGROUND Adverse drug reactions account for the highest proportion among the causes of morbidity and mortality in clinical wards and are posing a considerable challenge. Hence, the objective of this study was to find out the prevalence of adverse drug reactions and the factors which contribute to their prevalence. METHODS A prospective patient record review was carried out at a tertiary car...

BACKGROUND Previous studies of adverse drug events (ADE) as a cause of hospital admission in the elderly have often been limited in their ability to assess fully the impact and potential for prevention because they either did not include all categories of ADE and/or did not assess severity and preventability. AIMS To assess the frequency, severity and preventability of ADE causing emergency m...

CONTEXT Adverse drug events, especially those that may be preventable, are among the most serious concerns about medication use in older persons cared for in the ambulatory clinical setting. OBJECTIVE To assess the incidence and preventability of adverse drug events among older persons in the ambulatory clinical setting. DESIGN, SETTING, AND PATIENTS Cohort study of all Medicare enrollees (...

detection of adverse drug reactions (adrs) in hospitals provides an important measure of the burden of drug related morbidity on the healthcare system. spontaneous reporting of adrs is scare and several obstacles to such reporting have been identified formerly. this study aimed to determine the role of clinical pharmacy residents in adr reporting within a hospital setting.clinical pharmacy resi...

BACKGROUND Drug allergy represent an important subset of adverse drug reactions that is worthy of attention because many of these reactions are potentially preventable with use of computerised decision support systems. This is however dependent on the accurate and comprehensive recording of these reactions in the electronic health record. The objectives of this study were to understand approach...

The pharmacovigilance study was conducted in100 patients with pulmonary tuberculosis admitted pulmonology ward of Government general hospital, Anantapur, Andhra Pradesh. The purpose of this study is to assess the rate of adverse drug reactions induced by antitubercular drugs and also to detect serious and preventable ADRs.