We have previously shown that ~10% of all eukaryotic mRNAs contain potential programmed -1 ribosomal frameshifting (-1 PRF) signals and that some function as mRNA destabilizing elements through the Nonsense-Mediated mRNA Decay (NMD) pathway by directing translating ribosomes to premature termination codons. Here, the connection between -1 PRF, NMD and telomere end maintenance are explored. Func...

BACKGROUND Autologous platelet concentrate has been used to improve the function and regeneration of injured tissues. Tendinopathies are common in clinical practice, although long-term treatment is required. On the basis of lead time, we compared the effect of using platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in repairing rat Achilles tendon. METHODS The effectiveness of usi...

BACKGROUND Pulsed radiofrequency (PRF) application to the dorsal root ganglia can reduce neuropathic pain (NP) in animal models, but the effect of PRF on damaged peripheral nerves has not been examined. We investigated the effect of PRF to the rat sciatic nerve (SN) on pain-related behavior and SN ultrastructure following chronic constriction injury (CCI). METHODS The analgesic effect was mea...

The high squint diving SAR is widely used to provide the information in advance. Large squint angle deduces the deeper coupling of range and azimuth of SAR echoes which makes SAR imaging more difficult. Especially, the large range migration of the deep couple heavily burdens the imaging processing time and storage units. The diving motion of platform worsens the situation. This paper proposes t...

In tomato, resistance to Pseudomonas syringae pv. tomato (Pst) strains expressing the avirulence gene avrPto requires the presence of at least two host genes, designated Pto and Prf. Here we report that Prf encodes a protein with leucine-zipper, nucleotide-binding, and leucine-rich repeat motifs, as are found in a number of resistance gene products from other plants. prf mutant alleles (4) were...

Traditionally, modes of Message Authentication Codes(MAC) such as Cipher Block Chaining (CBC) are instantiated using block ciphers or keyed Pseudo Random Permutations(PRP). However, one can also use domain preserving keyed Pseudo Random Functions(PRF) to instantiate MAC modes. The very first security proof of CBC-MAC [BKR00], essentially modeled the PRP as a PRF. Until now very little work has ...

objectives : platelet preparations are commonly used to enhance bone and soft tissue regeneration. considering the existing controversies on the efficacy of platelet products for tissue regeneration, more in vitro studies are required. the aim of the present study was to compare the in vitro effects of plasma rich in growth factors (prgf) and platelet-rich fibrin (prf) on proliferation and viab...

background: various materials and techniques have been developed to facilitate bone healing process and reduce its healing period. in recent studies, it is pointed out that, platelet-rich fi brin (prf) which is derived autogenously from the own blood of the individuals, increase regeneration and accelerate the healing of the wound, due to the consisting various growing factors. the aim of the e...

BACKGROUND Choukroun's platelet-rich fibrin (PRF) is an autologous leukocyte- and platelet-rich fibrin biomaterial. The purpose of this study was to analyse the in vitro effects of PRF on human bone mesenchymal stem cells (BMSC), harvested in the oral cavity after preimplant endosteal stimulation. MATERIALS AND METHODS BMSCs from primary cultures were cultivated with or without a PRF membrane...