Adrenal Insufficiency (AI) is defined as deficient production or action of glucocorticoids resulting from either a structural damage of adrenal glands, namely ‘‘primary adrenal insufficiency’’, or an impairment of the hypothalamic-pituitary axis or ‘‘secondary adrenal disease’’ [1]. Primary AI is rare in general population, with an annual incidence of approximately 6/million adults/year and pre...

The incidence of primary adrenal lymphoma is a very rare. Primary adrenal lymphoma is usually suspected in a patient with bilateral adrenal masses, with/without lymphadenopathy and with/without any signs of adrenal insufficiency.1,2 The most common symptom observed in nearly 70% patients is presence of bilateral adrenal mass. Nearly 50% of the patients present with syndrome of adrenal insuffici...

A 74 year old women presented with lethargy and weight loss and was found to have profound adrenal insufficiency and bilateral adrenal mass lesions. Histological examination revealed non-Hodgkin's lymphoma. There was no evidence of lymphoma outside the adrenal glands. Isolated bilateral adrenal masses may rarely be due to primary adrenal non-Hodgkin's lymphoma, which is often associated with ad...

Adrenal insufficiency is a life-threatening condition that occurs secondary to impaired secretion of adrenal glucocorticoid and mineralocorticoid hormones. This condition can be caused by primary destruction or dysfunction of the adrenal glands or impairment of the hypothalamic-pituitary-adrenal axis. In children, the most common causes of primary adrenal insufficiency are impaired adrenal ster...

adrenal insufficiency is a life-threatening disorder which must be treated with glucocorticoid replacement and needs permanent dose adjustment during patient's different somatic situations. insufficient glucocorticoid doses result in adrenal crisis and must be treated with intravenous hydrocortisone. the patient was known with adrenal insufficiency and was treated optimally with fludrocortisone...

allgrove syndrome also known as triple-a syndrome is an autosomal recessive disorder characterized by alacremia, achalasia and acth-resistant adrenal insufficiency. although this syndrome is rare, herein we report four cases with different clinical manifestations. they were referred to the gastrointestinal ward during a one year period with complaints of vomiting and dysphagia. the diagnosis of...

the surgical intensive care unit is not an unusual event.1 Prompt recognition and management of adrenal insufficiency are critical to patient recovery and survival. Although it is an infrequent presenting sign of adrenal insufficiency, hypercalcemia is a well recognized complication of the disorder.2,3 Hypercalcemia has been reported to occur not only with primary hypoadrenalism but also with s...