نتایج جستجو برای: primary central nervous system lymphoma pcnsl
تعداد نتایج: 3162801 فیلتر نتایج به سال:
Primary central nervous system lymphoma (PCNSL) is a rare form of extranodal non-Hodgkin's lymphoma with continuously increasing incidence in both immunosuppressed and immunocompetent individuals. PCNSL is a very aggressive tumor with a poor outcome, and its clinical outcome is much worse than for nodal lymphomas. Differently from lymphomas arising in lymph nodes or in other extranodal sites, t...
Temozolomide (TMZ), an alkylating agent, is widely used for treating high-grade gliomas and has emerged as a treatment option for primary central nervous system lymphoma (PCNSL) because of its good penetration of the blood-brain barrier (BBB) and mild toxicity profile. To our knowledge, the role of temozolomide in the treatment of lymphoma was confined to PCNSL and its role in lymphoma central ...
Primary central nervous system lymphoma (PCNSL) is a relatively rare form of extra-nodal non-Hodgkin’s lymphoma that accounts for approximately 4% of primary central nervous system tumors. Treatment with high-dose methotrexate-based chemotherapeutic regimens have resulted in response rates of 60-70% or higher and long-term survival in 15-30% of patients. – 4 While PCNSL is sensitive to radiatio...
PURPOSE Primary central nervous system lymphoma (PCNSL) is an aggressive non-Hodgkin lymphoma confined to the central nervous system. Whether there is a PCNSL-specific genomic signature and, if so, how it differs from systemic diffuse large B-cell lymphoma (DLBCL) is uncertain. EXPERIMENTAL DESIGN We performed a comprehensive genomic study of tumor samples from 19 immunocompetent PCNSL patien...
The overall response rates and long-term survival of primary central nervous system lymphoma (PCNSL) are still significantly inferior to the results achieved in similar subtypes of extranodal non-Hodgkin's lymphoma. It is clearly necessary to investigate new therapeutic methods on PCNSL. We encountered three patients histologically documented PCNSL as diffuse large B-cell lymphoma (DLBCL). They...
A 65-year-old woman with a medical history significant for remote non-Hodgkin lymphoma presented with confusion and visual complaints. Magnetic resonance imaging showed a parietal-occipital mass with surrounding vasogenic edema. The patient underwent a stereotactic, parietal-occipital craniotomy and biopsy of the lesion. A diagnosis of primary central nervous system lymphoma was made on the bas...
PURPOSE Primary central nervous system lymphoma (PCNSL) is a rare disease. The index report describes a patient with intraocular lymphoma secondary to recurrent PCNSL and corresponding retinal findings on spectral domain optical coherence tomography (SD-OCT). METHODS Case report. RESULTS OCT changes were documented and correlated with the clinical course of intraocular lymphoma progression ...
Lymphomatosis cerebri (LC) is a rare form of primary central nervous system lymphoma (PCNSL). Little is known about cases of LC with spinal cord involvement. Among the 11 PCNSL patients treated in our hospital during a four-year period, we identified two cases of LC with spinal cord lesions. One showed a spinal cord lesion followed by leukoencephalopathy. The other showed a spinal cord lesion a...
Dr. Felipe Slaviero – Edifício das Clínicas Rua Teixeira Soares 885 / 10o andar 99010-901 Passo Fundo RS Brasil. E-mail: [email protected] Primary central nervous system lymphoma (PCNSL) is a form of extranodal non-Hodgkin’s lymphoma, which occurs in the brain, leptomeninges, spinal cord, or eyes. PCNSL is an uncommon intracranial neoplasm, particularly in the immunocompetent patient p...
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