results in a total of 40 sporadic prostate cancer and 80 benign prostatic hyperplasia cases, no xmrv was detected by real-time pcr and nested-pcr. rnase l r462q polymorphism analysis reveals that although there was an increase in the risk of prostate cancer correlated with the q/q allele of rnase l at position 462, the frequencies of the rnase l r462q alleles were not statistically significant ...

introduction: aim of this study was to assess the association between prostate calcification in transrectalultrasound (trus) and sono- guided needle biopsy in prostate cancer (pca). methods: a cross-sectional study was performed on patients referred to imam khomeini hospital between 2005 and 2011 who underwent trus biopsy due to increased psa or abnormal dre. the serum levels of psa, prostate v...

Background: In most cases, prostatitis can be caused by a bacterial agent such as Ureaplasma urealyticum. Considering to the cumbersome of the culture method for the detection of Ureaplasma species in clinical samples such as prostate; PCR method that is faster and more appropriate than the cultivation methods, can be utilized for the detection of <em...

best treatment option, although, there is no common consent on optimal therapy for advanced prostate cancer. case presentation: the present study reports a case of 75 year-old man who had a huge heterogeneous soft tissue mass lesion with non-homogeneous enhancement consisted low attenuated foci occupying pelvis cavity and lower abdomen with loss of mesenteric fat and invasion to posterior bladd...

Purpose: In the current study, using different radiobiological models, tumor control probability (TCP) and normal tissue complication probability (NTCP) of radiotherapy plans were calculated for three-dimensional conformal radiation therapy (3D-CRT) and intensity modulated radiation therapy (IMRT) of prostate cancer.Methods and Materials: 10 prostate plans were randomly selected among patients ...

there are increasing data on novel tumor markers such as gelatinase a, which play a key role in tissue invasion and metastasis. since prostate cancer is one of the common malignancies, we designed a simple and applicable indi¬rect hemagglutination (iha) test for determination of total gelatinase a in se¬rum samples. in this study, we have analyzed the circulating form of gelatinase a (mmp-2) in...

PURPOSE The Cooperative Prostate Cancer Tissue Resource (CPCTR) is a National Cancer Institute-supported tissue bank that provides large numbers of clinically annotated prostate cancer specimens to investigators. This communication describes the CPCTR to investigators interested in obtaining prostate cancer tissue samples. EXPERIMENTAL DESIGN The CPCTR, through its four participating institut...

Prostate cancer (PrCa) is highly heritable, and although rare variants contribute significantly to PrCa risk, few have been identified date. Herein, whole-genome sequencing was performed in a large family featuring multiple affected relatives spanning several generations. A rare, predicted splice site EZH2 variant, rs78589034 (G > A), as segregating with disease all but two individuals the fami...

Prostate gland is an accessory of the male reproductive system.Prostate begins development from mesenchymal tissue, surrounding urogenital sinus in 3 rd month gestation. Epithelial buds invaginate posterior on either side verumontanum. Concurrently, Wolffian ducts develop into seminal vesicles, epididymis, Vasdeferens and ejaculatory that are stimulated by fetal testosterone. Histologically all...

There are many techniques have been used in the surgical treatment of prostatitis, prostatic abscesses and prostatic cysts. Partial or complete prostatectomy, marsupialization, or debridement and drainage have all been advocated; unfortunately all of these techniques are associated with complications such as incontinence, cyst or abscess recurrence, etc. More recently, prostatic omentalization ...