background transurethral resection of the prostate (turp) is the most common surgical treatment for benign prostatic hyperplasia. objectives the aim of the present study was to compare the conventional bipolar transurethral resection of prostate (turp) with a modified transurethral resection of the prostate (m-turp) in men with mild to moderate symptoms of benign prostatic hyperplasia. patients...

Benign prostatic hyperplasia (BPH) represents a pattern of non-malignant growth of prostatic fibromuscular stroma. Metabolic disturbances such us pre-diabetes and metabolic syndrome may have a role in BPH pathophysiology. A potential explanation for the above relationship involves the insulin-like growth factor (IGF) axis as well as IGF binding proteins, (IGFBPs) of which the most abundant form...

BACKGROUND Prostatic oxidative stress (OS) is androgen-regulated and a key event in the development of prostate cancer (PC). Thus, reducing prostatic OS is an attractive target for PC prevention strategies. We sought to determine if the individual's prostatic OS status can be determined by examining the OS in surrogate androgen regulated tissues from the same host. METHODOLOGY/PRINCIPAL FINDI...

Purpose To evaluate the efficacy and safety of a minimally invasive treatment for benign prostatic hyperplasia (BPH) by transurethral dehydrated ethanol injection. Patients and method Eight patients with clinical symptoms of benign prostatic hyperplasia were evaluated by urodynamic study, cystoscope and transrectal ultrasound preoperatively. Under regional anesthesia, transurethral injection wa...

Objective- To compare transabdominal (TA) and transrectal (TR) ultrasonography of the prostate gland. Design- Experimental study. Animals- 10 intact male dogs that required euthanasia for reasons other than prostatic disease. Procedures- Prostatic length (L), width (W) and height (H) were measured in T A (L1, W1 and H1) and TR (L2 and H2...

Background & Objective: Some prostatic lesions contain small suspicious foci for prostatic carcinoma in which the morphological features are equivocal. Two immunohistochemical markers namely, cytokeratin 34 beta E12 (Ck34βE12) and α-Methylacyl-CoA racemase (AMACR), were evaluated in these lesions for a definitive diagnosis and avoiding misdiagnosis or overdiagnosis of prostatic...

Prostatic biopsies provide abundant information for diagnosis of prostatic cancer. Whereas, inspection in the vast biopsy images under the microscope is a heavy loading to pathologists. Besides, human grading is always subjective to interand intra-observer variability. Automatic inspection for prostatic biopsy image is thus necessary. In this paper, we proposed a novel approach to automatically...

this study was aimed at determining intra and inter-observer concordance rates in the gleason scoring of prostatic adenocarcinoma, before and after a web-based educational course. in this self-controlled study, 150 tissue samples of prostatic adenocarcinoma are re-examined to be scored according to the gleason scoring system. then all pathologists attend a free web-based course. afterwards, the...

BACKGROUND Genetically engineered mouse models are essential to the investigation of the molecular mechanisms underlying human prostate pathology and the effects of therapy on the diseased prostate. Serial in vivo volumetric imaging expands the scope and accuracy of experimental investigations of models of normal prostate physiology, benign prostatic hyperplasia and prostate cancer, which are o...