PURPOSE To determine the functional defects in two male patients with progressive cone dystrophy and hybrid L-M cone pigment genes. METHODS Clinical evaluation, standard electroretinography, and electrooculography were performed in two affected patients and two family members. Measurements of spectral sensitivity and transient tritanopia were made in both patients. RESULTS In the patients, ...

AIM To provide a simple test that detects the onset of age related maculopathy (ARM), and can be used to monitor its severity. METHODS Colour contrast sensitivity was measured using computer graphics techniques. Colour thresholds were measured along tritan and protan colour confusion axes in the presence of dynamic luminance noise. Thresholds were determined separately for two sizes of optoty...

Wavelength sensitivity was measured in the guppyfish by means of optomotor responses to a special apparent-motion display. A set of red and green bars appeared to humans to move to the left if red was darker than green, but to the right if red was lighter than green. At equiluminance there was no apparent motion. By noting the direction in which the fish swam to follow the stripes we were able ...

Early visual changes caused by diabetes include color vision losses and an abnormal full-field electroretinogram. The purpose of this study was to evaluate color vision in type 2 diabetic patients with no clinically detectable retinopathy using an objective psychophysical color vision test, evaluate retinal function assessed by full-field electroretinography (ffERG), and verify the agreement am...

In the past, equine color vision was tested with stimuli composed either of painted cards or photographic slides or through physiological testing using electroretinogram flicker photometry. Some studies produced similar results, but others did not, demonstrating that there was not yet a definitive answer regarding color vision in horses (Equus caballus). In this study, a pseudoisochromatic plat...

PURPOSE To investigate the influence of color vision on myopia development by testing refraction error and axial length of the eye for high school students with and without color vision deficiency (CVD). METHODS A school-based cross-sectional, cluster sample study was conducted to test the color vision and refractive error of 16,539 high school students. Students were screened for CVD using a...

Purpose Progressive retinal ganglion cell (RGC) loss is the pathological hallmark of autosomal dominant optic atrophy (DOA) caused by pathogenic OPA1 mutations. The aim of this study was to conduct an in-depth psychophysical study of the visual losses in DOA and to infer any selective vulnerability of visual pathways subserved by different RGC subtypes. Methods We recruited 25 patients carryi...