Mouth-exhaled hydrogen cyanide (HCN) concentrations have previously been reported to originate from the oral cavity. However, a direct correlation between the HCN concentration in oral fluid and in mouth-exhaled breath has not been explicitly shown. In this study, we set up a new methodology to simultaneously measure HCN in the headspace of oral fluid and in mouth-exhaled breath. Our results sh...

…upon being put into a solution of nicotine in sea water, the squid, 3 or 4 seconds, falls to bottom dish… Moore, 1919 Nicotine influences physiology organism via CNS.1 As confirmed also subiculum, may directly modulate hyperpolarization-activated cyclic nucleotide–gated (HCN) non-selective cation channel.2 The latter mirrors findings interneurons stratum oriens (SO) with axons terminating with...

ion channels play a major role in the regulation of t cell function in health and disease. in a computer-based model, established to simulate t cells’ membrane potential (vm) generation, we discovered a discrepancy between the simulation and patch-clamp recordings. the predicted vm was more hyperpolarized than the measured vm, indicating that a yet unknown, depolarizing ion current might contri...

We report a sensitive search for the HCN(J=2→1) emission line towards SDSS J114816.64+525150.3 (hereafter: J1148+5251) at z=6.42 with the Very Large Array (VLA). HCN emission is a star formation indicator, tracing dense molecular hydrogen gas (n(H2) ≥ 10 4 cm) within star-forming molecular clouds. No emission was detected in the deep interferometer maps of J1148+5251. We derive a limit for the ...

the protease enzyme breaks down protein into amino acids as its constructors. protease immobilization onto appropriate support materials plays an essential role in various fields of technology including the food and detergent industries. accordingly, improvement of protease immobilization has been highly regarded due to its applications in bio catalysis. alginate and chitosan are natural polysa...

conclusions in this study, we isolated b. licheniformis producing an organic solvent-stable protease from oil-contaminated soil. the protease was stable and active in various organic solvents. by purification, the protease could be used as a biocatalyst for organic solvent-based enzymatic synthesis. results according to 16srdna sequencing, strain isa9 was identified as a new strain of bacillus ...

It is suggested that the incorporation of HCN in Titan’s atmospheric haze may be an important process affecting the HCN profile and the C/N ratio in Titan’s haze. By introducing a loss to the haze term for HCN (i.e. a production term of “poly-HCN”) in the photochemical model of Lara et al. (1996), we have improved the model’s ability to simultaneously reproduce the observed HCN and C2 hydrocarb...

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are activated by membrane hyperpolarization that creates time-dependent, inward rectifying currents, gated by the movement of the intrinsic voltage sensor S4. However, inward rectification of the HCN currents is not only observed in the time-dependent HCN currents, but also in the instantaneous HCN tail currents. Inward rectific...

Ghose and Desai [1] introduced a new interconnection for large-scale distributed memory multiprocessors called the Hierarchical Cubic Network (HCN). The HCN is topologically superior to a comparable hypercube. They also proposed optimal routing algorithms for the HCN and obtained its diameter, which is about three-fourths the diameter of a comparable hypercube. However, their routing algorithm ...