CONTEXT Proton spectroscopy has been recognized as a safe and noninvasive diagnostic method that, coupled with magnetic resonance imaging techniques, allows for the correlation of anatomical and physiological changes in the metabolic and biochemical processes occurring within previously-determined volumes in the brain. There are two methods of proton magnetic resonance spectroscopy: single voxe...

a rapid, specific and accurate proton quantitative nuclear magnetic resonance spectroscopic (1h qnmr) and also a reversed phase derivatization hplc method have been developed to quantify a toxic, uv-visible inactive and non-volatile impurity n,n-dimethylamine hydrochloride (dma∙hcl) in metformin hydrochloride (mf∙hcl), an active pharmaceutical ingradient. the method is based on proton quantitat...

lipomatosis of the nerve, also known as fibrolipomatous hamartoma, is characterized by the infiltration of the nerve by fibro-fatty tissue. the affected nerve becomes thicker, and it simulates a mass lesion. lipomatosis usually affects the median nerve and lipomatosis of the sciatic nerve is extremely rare. magnetic resonance imaging (mri) is the key to diagnosis, and it is usually pathognomoni...

conclusion these data indicate that while ce-mri will depict more positive results, there are cases in which dwi will show a positive result while ce-mri is negative. we suggest that the combination of these two imaging modalities might yield more positive results in diagnosing acute ms attack giving rise to a more accurate diagnosis. results ce-mri yielded positive results for 61 (87%) patient...

the application of magnetic resonance to diagnostic medical imaging stands as one of the great scientific achievements in the past 50 years. magnetic resonance techniques are easily applied to organs which remain stationary during the imaging procedure, such as the brain and musculoskeletal system. imaging of moving heart structures and circulating blood is considerably more difficult.   clinic...

We identified eight patients with a distinct magnetic resonance imaging pattern of inhomogeneous cerebral white matter abnormalities and selective involvement of brainstem and spinal tracts. Proton magnetic resonance imaging showed increased lactate in the abnormal white matter. Clinically, the patients had slowly progressive pyramidal, cerebellar, and dorsal column dysfunction. The uniform, hi...

Metallic and superparamagnetic DNA-templated nanoparticle (NP) chains are examined as potential imaging agents. Proton relaxation times (T(1) and T(2)) are measured for DNA nanostructures using nuclear magnetic resonance (NMR) spectroscopy. The layer-by-layer (LBL) method was used to encapsulate the DNA-templated NP chains and demonstrated a change in proton relaxation times. Results from this ...

nowadays brain tumors remain as a significant cause of morbidity and mortality and are often treatment refractory. the grading of brain tumor has an important implication in clinical management. currently, magnetic resonance spectroscopy (mrs) is an important modality in evaluating and grading brain tumors. the aim of this study is  evaluation of metabolites in the differentiation of brain tumo...

background : magnetic resonance imaging of the breast is becoming a useful adjunct to mammography and sonography for the detection of breast lesions. however, it is not yet accepted as a routine examination for all breast cancer patients due to the lack of data regarding whether breast magnetic resonance imaging impacts recurrence or survival. this trial examines the use of magnetic resonance i...