background: hadron therapy for malignant tumor is becoming increasingly popular. there are many factors which effect on implementation of a proper treatment planning. the purpose of this work is to investigate the inhomogeneity effects as affecting factor on proton range, full width at half maximum (fwhm) and 20% position of penumbra (p20) by mcnpx code. materials and methods: an inhomogeneous ...

background: the advantages of proton beam in radiation therapy- like small lateral scattering as well as absence of exit dose tail in the organs which are after the tumor- make it capable of delivering more treatment doses to the target and much lesser to the critical tissues near it. materials and methods: in this study, the monte carlo mcnpx code has been used to simulate a slab head phantom ...

Alsanea, Fahed M. M.S., Purdue University, May 2014. Feasibility of Pulsed Proton Induced Acoustics for Dosimetry. Major Professor: Keith Stantz. Proton therapy has the potential to deposit its energy in tissue with high conformity to the tumor and significantly reduced integral dose to normal tissue compared to conventional radiation, such as x-rays. As a result, local control can be enhanced ...

Introduction: One crucial point when calculating the distribution of doses with ions is the uncertainty of the Bragg peak. The proton ranges in determined geometries like homogeneous phantoms and detector geometries can be calculated with a number of various parameterization models. Several different parameterizations of the range-energy relationship exist, with different level...

In this study, a comparison was made between a plastic scintillator (BC400), a Faraday Cup (FC) and an ionization chamber (IC) used for routine proton dosimetry. Thin scintillators can be applied to proton dosimetry and consequently to proton therapy as relative dosimeters because of their water-equivalent nature, high energy-light conversion efficiency, low dimensions and good proportionality ...

The Proton Therapy Facility at TRIUMF is now in routine operation treating ocular tumours using 70 MeV protons extracted from the 500 MeV H cyclotron. This paper describes the proton beam line, treatment control and dosimetry systems which are designed to provide accurate treatment dose delivery. The reproducibility of the shape and range of the unmodulated Bragg peak for various operating cond...

BACKGROUND In radiation therapy with ion beams, lateral distributions of absorbed dose in the tissue are important. Heavy ion therapy, such as carbon-ion therapy, is a novel technique of high-precision external radiotherapy which has advantages over proton therapy in terms of dose locality and biological effectiveness. METHODS In this study, we used Monte Carlo method-based Geant4 toolkit to ...

As proton therapy becomes increasingly popular, so does the need for Monte Carlo simulation studies involving accurate beam line modeling of proton treatment units. In this study, the 24 beam configurations of the Mevion S250 proton therapy system installed recently at our institution were modeled using the TOolkit for PArticle Simulation (TOPAS) code. Pristine Bragg peak, spread out Bragg peak...