BACKGROUND There is no information on the effects of the breed, gender and age on the cellular content and growth factor (GF) release from equine pure-platelet rich plasma (P-PRP) and pure-platelet rich gel (P-PRG). The objectives of this study were: 1) to compare the cellular composition of P-PRP with whole blood and platelet poor plasma (PPP); 2) to compare the concentration of transforming G...

Introduction. The case report describes the effect of combination therapy using adipose-derived stem cells (ADSC), platelet-rich plasma (PRP) and platelet-poor (PPP) in treatment a maxillary cyst. Case outline. A cyst between central incisors was identified healthy 54-year-old male patient during routine dental check-up. Following thorough clinical radiographic examinations, plan presented expl...

INTRODUCTION: Activated platelets are known to release many kinds of growth factors such as Platelet Derived Growth Factor (PDGF) and Transforming Growth Factor-β (TGF-β). Platelet-rich plasma (PRP) is a fraction of plasma in which platelets are concentrated and is reported to be utilized as a source of multiple growth factors that promote tissue repair. Recent studies has shown that platelet r...

To the Editor: We read with interest the comments of Lippi et al (1 ) who questioned the reproducibility and difficulty of standardization when we (2 ) used platelet-rich plasma (PRP) in the thrombin generation assay (TGA). We evaluated the use of TGA to identify patients needing further specific thrombophilic risk factor testing (2 ). For this, we used frozen-thawed (ftPRP). PRP was obtained b...

BACKGROUND There is a lack information on the effects of the most commonly used anticoagulants for equine platelet rich plasmas (PRPs) elaboration on cell counts and growth factor release from platelet rich gels (PRGs). The aims of this study were 1) to compare the effects of the anticoagulants sodium citrate (SC), acid citrate dextrose solution A (ACD-A) and ACD-B on platelet (PLT), leukocyte ...

BACKGROUND To evaluate the efficacy of a single platelet-rich plasma (PRP) injection in reducing the return to sport duration in male athletes, following an acute hamstring injury. METHODS A randomised, three-arm (double-blind for the injection arms), parallel-group trial, in which 90 professional athletes with MRI positive hamstring injuries were randomised to injection with PRP-intervention...

BACKGROUND Platelet-rich plasma (PRP) has been used to augment tissue repair and regeneration after musculoskeletal injury. However, there is increasing clinical evidence that PRP does not show a consistent clinical effect. Purpose/Hypothesis: This study aimed to compare the effects of the following non-neutrophil-containing (leukocyte-poor) plasma fractions on human skeletal muscle myoblast (H...

OBJECTIVE Platelet-rich plasma (PRP) can promote wound healing. To observe the effect of PRP injection on the early healing of rat's Achilles tendon rupture so as to provide the experimental basis for clinical practice. METHODS Forty-six Sprague Dawley rats were included in this experiment, female or male and weighing 190-240 g. PRP and platelet-poor plasma (PPP) were prepared from the heart ...

Platelet-rich plasma (PRP) has a pool of multiple growth factors efficient at inducing the proliferation and osteogenic differentiation of human adipose-derived stem cells (hADSCs). Bone morphogenetic protein (BMP)-2 is a strong stimulator for the osteogenic differentiation of hADSCs. The purpose of this study was to verify the effect of PRP-released growth factors and microsphere-encapsulated ...

Clot structure is greatly influenced by a number of factors in vivo, calcium concentration being one of them. A pilot study with 10 healthy individuals was performed to investigate the effect of added calcium, in combination with plasma platelet concentration, on the turbidity of clots. Using a UV-Vis spectrophotometer, absorbance of both platelet-rich and platelet-poor clots was taken at 405 n...