BACKGROUND AND OBJECTIVES Many surface proteins are implicated in nasopharyngeal colonization and pathogenesis of Streptococcus pneumoniae. Some of these factors are candidate antigens for protein based vaccines. New vaccine designs focus on the surface proteins (e. g., pspA and pspC) and also cytolysin, and pneumolysin. In this study, 3 key virulence genes, lytA, pspC, and rrgA, which encoded ...

During a systematic search for periodic signals in a sample of ROSAT PSPC (0.1– 2.4 keV) light curves, we discovered ∼ 12 min large amplitude X–ray pulsations in 1WGA J1958.2+3232, an X–ray source which lies close to the galactic plane. The energy spectrum is well fit by a power law with a photon index of 0.8, corresponding to an X–ray flux level of ∼ 10−12 erg cm−2 s−1. The source is probably ...

Purple sweet potato color (PSPC), a naturally occurring anthocyanin, has a powerful antioxidant activity in vitro and in vivo. This study explores whether PSPC has the neuroprotective effect on the aging mouse brain induced by D-galactose (D-gal). The mice administrated with PSPC (100 mg/kg.day, 4 weeks, from 9th week) via oral gavage showed significantly improved behavior performance in the op...

A new reactor, the pulsed sieve plate column (PSPC), was developed to perform continuous emulsion polymerization reactions. This reactor combines the enhanced flexibility of tubular reactors with the mixing behavior provided by sieved plates and by the introduction of pulses that is important to prevent emulsion destabilization. The main objective of this work is to study the kinetics of vinyl ...

Abstract Widely used in chemical product manufacture, 1,4-dioxane is one of the emerging contaminants, and it poses great risk to human health ecosystem. The aim this study was degrade 1,4-dioxiane using a pulsed switching peroxi-coagulation (PSPC) process. electrosynthesis H2O2 on cathode Fe2+ production iron sacrifice anode were optimized enhance degradation. Under current densities 5 mA/cm2 ...

Prolonged and intensive exercise induces transient immunosuppression and is associated with an increased risk and severity of infections. The goal of this study was to characterize the antiviral and antibacterial properties of the bioactive metabolites of a blueberry-green tea-polyphenol soy protein complex (PSPC) in the serum of supplemented subjects during a 3-day intensified training period....

Increased nasopharyngeal colonization density has been associated with pneumonia. We used experimental human pneumococcal carriage to investigate whether upper respiratory tract viral infection predisposes individuals to carriage. A total of 101 healthy subjects were screened for respiratory virus before pneumococcal intranasal challenge. Virus was associated with increased odds of colonization...

Expression of the pspABCDE operon of Escherichia coli is induced upon infection by filamentous phage and by many other stress conditions, including defects in protein export. Expression of the operon requires the alternative sigma factor sigma54 and the transcriptional activator PspF. In addition, PspA plays a negative regulatory role, and the integral-membrane proteins PspB and PspC play a pos...

The immunomodulating action of two mushroom antitumor polysaccharides, polysaccharide-protein complex (PSPC) and lentinan, was elucidated through analysing the expression profile of cytokines during a time course (0 h to 48 h) after their administration. Among the 5 cytokine genes, the induction of a marked increase in the mRNA levels of IL-1alpha, IL-1beta, TNF-alpha, IFN-gamma and M-CSF by PS...

Abstract In this contribution, we present the stratigraphy of igneous and metamorphic rocks Taquetren Range, a sector located in southernmost margin North Patagonian Massif (42°42′00″ S - 69°30′00″ W). Its basement is composed newly defined “Lagunita Salada Igneous-Metamorphic Complex” (LSIMC), “Paso del Sapo Plutonic (PSPC) “Sierra de (STPC). The LSIMC comprises gneisses, schists, amphibolites...