Infection with Brucella spp. continues to pose a human health risk globally despite strides in eradicating the disease from domestic animals. Brucellosis has been an emerging disease since the discovery of Brucella melitensis by Sir David Bruce in 1887. Although many countries have eradicated B. abortus from cattle, in some areas B. melitensis and B. suis have emerged as causes of this infectio...

Rickettsial diseases are generally classified under the causes of pyrexia of unknown origin (PUO) and high prevalence of this disease is found in developing countries like India. Diagnosis in such cases is difficult because early sign and symptoms are non-specific and varied. Mortality may be as high as 3040% if untreated. Weil Felix in one of the cheapest screening method available for laborat...

OBJECTIVE The objective was to study megaloblastic anemia as a cause of pyrexia of unknown origin (PUO). MATERIALS AND METHODS We conducted a study on 15 patients of megaloblastic anemia associated with fever, attending our hospital clinics over a period of 6 months. RESULTS While 11 patients had symptoms suggesting foci of infection and responded well to intravenous antibiotics, 4 patients...

Prolonged unexplained fever is one of the most challenging problems encountered in clinical medicine. We report the case of a patient with an uncommon cause of Pyrexia of Unknown Origin (PUO).

OBJECTIVE To identify the correct site to biopsy in a case of pyrexia of unknown origin (PUO) caused by hepatic tuberculosis (TB). CLINICAL PRESENTATION AND INTERVENTION A 58-year-old man who developed hepatic TB presented with PUO. Ultrasonography (US) and computed tomography (CT) of the abdomen showed only calcifications in the liver, and positron emission tomography (PET)/CT showed diffuse...

We perform the BFV-BRST quantization of fourth-order Pais-Uhlenbeck oscillator (PUO) for first time. show that although PUO is not naturally constrained in sense Dirac-Bergmann, it possible to profit from introduction suitable constraints phase space order obtain a proper BRST invariant quantum system. Starting its second-class system description, we use BFFT formalism first-class as gauge symm...

Pyrexia of unknown origin (PUO) in a patient with acquired immunodeficiency syndrome (AIDS) is a challenging clinical problem despite recent advances in the diagnostic modalities. The diagnosis of the cause of fever is especially difficult in the postoperative period as the focus remains on the operative site. We present an unusual cause of PUO in a patient with advanced HIV disease during an i...

The nucleotide sequence and the deduced amino acid sequence for the genes encoding the structural proteins of two strains of dengue virus type 2 (DEN-2) were determined from cDNA clones. The genes for C, prM(M) and E proteins were sequenced for the prototype DEN-2 virus, the New Guinea C strain. Also sequenced were the prM(M) and E genes of PUO-218. This strain of DEN-2 was isolated during 1980...

Background: Whipple’s disease is a rare bacterial infection caused by bacterium Trophyrema Whipplei that most often affects digestive system mainly duodenum and joints. interferes with normal digestion impairing the breakdown of foods hampering body’s ability to absorb nutrients such as fats carbohydrates. Histopathological characteristics overlap other diseases (such mycobacterial infections, ...

Splenic tuberculosis is an extremely rare clinical entity and a frequently forgotten cause of pyrexia of unknown origin (PUO). We present the case of a 42 year old man who presented with fever of unknown origin. Ultrasonography revealed multiple hypoechoic areas within the spleen. As the abscesses did not respond to broad spectrum antibiotics splenectomy was done. The excised organ showed multi...