Analogs of the luteinizing hormone releasing hormone (LHRH) having a moiety (D-Qal-) of/3-(3-quinolyl)-D-a-alanine were synthesized toward more effective inhibitors of ovulation. [N-Ac-^Cl-D-Phe1-2, D-3-Pal3, D-3-Qal6, D-Ala10]-LHRH was the most effective, and had an antiovulatory activity of 40% at 1 /ig/rat. D-3-Qal6 was as effective as D-Trp6 in combination with N-Ac-z1 Pro1, ^oF-D-Phe2, D-T...

In the clinical trials of chronic diseases such as cancer or AIDS, it has been increasingly recognized that it is not enough just to consider simple time to event end points. For example, a new experimental drug may prolong overall survival time of patients, but in the meantime, it can be toxic for a longer period of time. Therefore, the trade-off between the quality and quantity of life of pat...

The protection of urban heritage is not an abstract intellectual theory, as it resembles any planning process subject to a set factors. Those factors are determined in progressive and continuous way by the actors this field. If political decision was considered main motor its dimensions objectives, technical factor less important, embodied these objectives. In context study came approximate bet...

kooh-e khajeh (kajeh mountain), with 120m height and 2-2.5km in diameter, is located at hamoon lake like an island. since the archaic era, due to its specific geopolitical location, religious sacredness, and the natural beauty especially at the times of water-richness at hamoon, this place caused the formation of settlements. based on an intensive archaeological survey conducted in this region...

We examine the gas kinematics of the LMC revealed by the high spatial and velocity resolution H I data cube of the combined ATCA and Parkes telescope surveys. We adopt an approach designed to facilitate comparisons with quasar absorption line observations, in particular restricting our analysis to pointings with H I column density satisfying the damped Lyα (DLA) criterion. We measure velocity w...

In order to determine the factors of decay and sourness fig fruits, in summer 2016-17, 60 leaf, fruit stem samples from different regions Tehran, Varamin (Qal'e No), Mazandaran (Amol, Noor Sari), Lorestan Iran a branch sample Italy were collected. We obtained 30 isolates sample. The pathogenicity confirmed by artificially inoculation using fruits. They also characterized based on key ph...

A series of Thy-1.2+ Ly-1+ Qa-1+ malignant T cell clones have been isolated from murine sarcoma virus-murine leukemia-Moloney (MSV-MuLV-M)-induced B cell lymphomas or from MSV-MuLV-M-infected B6 mice. These T cell clones enhance both antigen-independent and -dependent lymphocyte differentiation and function. They also induce the differentiation of granulocytes and erythrocytes in the stem cell ...

Let me first enter a disclaimer with respect to the title of this chapter. Artificial intelligence is an apparently selfevident phrase which has comf jhto common usage without having a well defined and gprierally accepted meaning. Unfortunately, this term $£$$ . carries with it certain anthropomorphical implicaf>6^^ which tend to arouse emotional responses on theTpgft of the reader that have li...