Semiran city-castle consists of a series monuments dated in the 10th century AD1, located on banks Qezel Owzan River, north-western Iran. On this river, Sefid-rud Dam has been built (1956-1962), behind which lake developed. At time its dewatering, it turned landscape into peninsula, causing significant damage to ancient sites. The following study presents results an archaeological survey, made ...

Timing and Amplitude of Wave Reflection To the Editor: Dr Mitchell is to be complemented on a perceptive, articulate editorial on detection and interpretation of wave reflection in the human arterial system.1 While we have differed in the past, modification of 2 points would bring his views into line with ours. First, we see no specific implication of “impedance matching” (increasing proximal a...

Background: Alport’s syndrome includes a group of heterogeneous inherited disorders involving the basement membranes of the kidney and may involve the cochlea and the eye. It is a progressive renal disease characterized by hematuria and progressive renal failure that is often accompanied by sensorineural deafness and/or ocular abnormalities mainly macular flecks and lenticonus. The heterogeneit...

At the center of this work is analysis consequences implementing Joint Comprehensive Plan Action (also known as - Iran nuclear deal) on divergent foreign policy approaches main indicators mismatch in relations between United States and European Union during administration 45th US President Donald Trump. While unilaterally withdrew from agreement, EU member states remained it. The Union, one han...

Background: Systemic sclerosis (SSc) is a multisystemic disease featured by vascular and immunological disorders along with an excessive accumulation of the components connective tissue that cause cutaneous fibrosis different organs. The occurrence endothelial dysfunction together indicates cell-derived factors, such as endothelin-1 (ET-1), may have important role in pathogenesis SSc. upregulat...

Two compounds in development in the oncology therapeutic area, bearing similar structural cores, had pronounced differences in human pharmacokinetics (exposure). Investigative studies in human liver microsomes identified an NADPH independent metabolite. Studies in hepatic S9 and cytosol fractions in the absence and presence of menadione as well as metabolite structure, implicated the involvemen...

What is the basis of the human capacity for language: Is language shaped only by sensorimotor constraints and experience, or are some aspects of language universal, abstract, and potentially amodal? The set of papers assembled in this collection represent state of the art research on this age-old set of questions. To gauge the universality of language structure and its abstraction, the first gr...