The ability of the hydrosoluble ruthenium(II) complexes [RuCl2(h-arene)(PTA)] 3a–d, [RuCl2(h-arene)(PTA-Bn)] 4a–d, [RuCl2(h-arene)(DAPTA)] 5a–d, [RuCl2(h-arene)(TPPMS)] 6a–d (arene = C6H6, p-cymene, 1,3,5-C6H3Me3, C6Me6) to promote the atom-economic formation of b-oxo esters, by addition of carboxylic acids to terminal propargylic alcohols in water has been explored. Scope, limitations and cata...

The first synthesis of a monohydroxy pillar[5]arene has been carried out, by controlling the de-O-methylation of per-methylated pillar[5]arene. Using monohydroxy pillar[5]arene as an intermediate, mono-guest-functionalized pillar[5]arene was prepared. It formed a self-inclusion complex in CDCl(3) whereas in acetone-d(6) dethreading of the guest moiety took place.

BACKGROUND The new ruthenium(II)-arene complex, which bearing a carborane unit, ruthenium and ferrocenyl functional groups, has a novel versatile synthetic chemistry and unique properties of the respective material at the nanoscale level. The ruthenium(II)-arene complex shows significant cytotoxicity to cancer cells and tumor-inhibiting properties. However, ruthenium(II)-arene complex of mechan...

A series of six Ru(arene) complexes, [(η(6)-p-cymene)Ru(dpb)(py-R)](2+) (1-6, dpb = 2,3-bis(2-pyridyl)benzoquinoxaline, py-R = 4-substituted pyridine, R = N(CH3)2, NH2, OCH3, H, COOCH3 and NO2), were synthesized and their photochemical and photobiological properties were compared in detail. The electron push/pull character of the R groups has a significant impact on both ligand photodissociatio...

Diffuse reflectance and luminescence techniques were used to study the photophysics and photochemistry of pyrene within p-tert-butylcalix[n]arenes with n = 4, 6, and 8, and to study their ability to form inclusion complexes in heterogeneous media. Evidences for inclusion complex formation were found for the three hosts under study. Ground state diffuse reflectance results have shown the formati...

Cationic titanium(IV) complexes with ansa-(eta(5)-cyclopentadienyl,eta(6)-arene) ligands were synthesized and characterized by X-ray crystallography. The strength of the metal-arene interaction in these systems was studied by variable-temperature NMR spectroscopy. Complexes with a C(1) bridge between the cyclopentadienyl and arene moieties feature hemilabile coordination behavior of the ligand ...

This work is the first in-depth study of osmium binding to DNA and confirms the pharmacological activity of a new class of anticancer metallodrugs. We investigated the interactions between the potential biological target DNA and four osmium(II) arene complexes, of the type [(eta 6-arene)Os(LL)Cl]n+, where arene = biphenyl or p-cymene and LL = ethylenediamine, picolinate, or oxinate in an effort...

Arene ruthenium complexes [(h-arene)Ru(sacc)2(OH2)] (arene 1⁄4 para-cymeme, benzene) containing an aqua and two saccharinato ligands have been synthesized from [(h-arene)RuCl2]2 and sodium saccharinate in a water-ethanol mixture (1:1). The aqua complex [(h-MeC6H4Pr)Ru(sacc)2(OH2)] reacts with acetonitrile to give the acetonitrile complex [(h-MeC6H4Pr)Ru(sacc)2(NCMe)]. The corresponding benzene ...

Highly enantiomerically enriched (h-arene)tricarbonylchromium(0) complexes whose chirality originates from the 1,2disubstitution pattern of the arene and the coordination of the metal to one enantiotopic face of the arene are powerful chirons in asymmetric synthesis. Robust, planar chiral arene complexes also increasingly find application as chiral ligands in asymmetric catalysis. Enantiomerica...

p-tert-Butylcalix[8]arene-octaacetic acid octaethyl ester and calix[8]arene-octaacetic acid octaethyl ester well recognized 2-phenylethylamine and phenylalanine methyl ester compared with the corresponding calix[6]arene derivatives. Moreover, the calix[8]arene derivatives, especially one having tert-butyl groups, gave better selectivity against biologically active amines having a complicated st...